Rapid, Multiplex Optical Biodetection for Point-of-Care Applications

  • Frank Y. S. Chuang
  • Bill W. ColstonJr.
Part of the Springer Series on Chemical Sensors and Biosensors book series (SSSENSORS, volume 1)


Despite hopes that antibiotic and vaccine therapies might one day lead to the complete eradication of infectious disease [1], new and emergent pathogens continue to pose a global threat to public health [2]. Even in the present day, infectious disease remains among the top ten causes of death in the United States for all age groups [3]. In part due to increased virulence of recent strains, but also due to a growing cohort of individuals susceptible to severe infection, the U.S. mortality rate caused by influenza has risen to roughly 36,000 per year, exceeding the current rate of HIV/AIDS related deaths in the country [4, 5]. While the victories over bubonic plague (Yersinia pestis), whooping cough (Bordetella pertussis), polio and smallpox (variola) are clearly significant, new diseases represented by human immunodeficiency virus (HIV), as well as the tragic reality of biological agents used as weapons of terrorism and mass destruction [6] — offer sobering evidence that the battle against infectious disease is far from over [7].


Respiratory Syncytial Virus Capture Antibody Gene Chip Charge Couple Device Camera Yersinia Pestis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2004

Authors and Affiliations

  • Frank Y. S. Chuang
  • Bill W. ColstonJr.

There are no affiliations available

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