Skip to main content

Nierenkrankheiten

  • Chapter
Neugeborenenintensivpflege
  • 85 Accesses

Zusammenfassung

In der Neonatalperiode ist die Nierenfunktion im Vergleich zu älteren Kindern und Erwachsenen noch eingeschränkt (Tabelle 13–1). Bedingt durch einen hohen renalen Gefäßwiderstand sind während der Fetalzeit der renale Blutfluß und damit die glomeruläre Filtrationsrate (GFR) niedrig. Nach der Geburt sinkt der renale Gefäßwiderstand, renaler Blutfluß und GFR steigen in den ersten Lebensmonaten kontinuierlich an. Erwachsenenwerte werden mit etwa 18 Monaten erreicht. Da Kreatinin im Tubulus weder resorbiert noch sezerniert wird, stellt die Kreatininclearance ein Maß für die GFR dar (Tabelle 13–2).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 54.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Adelman RD (1988) The hypertensive neonate. Clin Perinatol 15: 567–585

    PubMed  CAS  Google Scholar 

  2. Adhikari M, Moodley M, Desai PK (1990) Mannitol in neonatal cerebral oedema. Brain Dev 12:349–351

    Google Scholar 

  3. Al-Orifi F, McGillivray D, Tange S, Kramer MS (2000) Urine culture from bag specimens in young children: are the risks too high? J Pediatr 137:221–226

    Article  PubMed  CAS  Google Scholar 

  4. Anand SK (1991) Hypertension. In: Taeusch HW, Ballard RA, Avery ME (eds) Diseases of the newborn. 6th edn. Saunders, Philadelphia

    Google Scholar 

  5. Arant BS (1981) Nonrenal factors influencing renal function during the neonatal period. Clin Perinatol 8:225–240

    PubMed  CAS  Google Scholar 

  6. Aya K, Tanaka H, Seino Y (2000) Novel mutation in the nephrin gene of a Japanese patient with congenital nephrotic syndrome of the Finnish type. Kidney Int 57:401–404

    Article  PubMed  CAS  Google Scholar 

  7. Bökenkamp A, von Kries R, Nowak-Göttl U, Göbel U, Hoyer PF (2000) Neonatal renal venous thrombosis in Germany between 1992 and 1994: Epidemiology, treatment and outcome. Eur J Pediatr 159:44–48

    Article  PubMed  Google Scholar 

  8. Brion LP, Campbell DE (2000) Furosemide for symptomatic patent ductus arteriosus in indomethacin-treated infants. Cochrane Database Syst Rev CD001148

    Google Scholar 

  9. Brion LP, Primhak RA, Ambrosio-Perez I (2000) Diuretics acting on the distal renal tubule for preterm infants with (or developing) chronic lung disease. Cochrane Database Syst Rev CD001817

    Google Scholar 

  10. Burghard R, Leititis JU, Brandis M (1987) Nierenfunktionsstörungen und akutes Nierenversagen bei Neugeborenen. Monatsschr Kinderheilkd 135:10–21

    PubMed  CAS  Google Scholar 

  11. Chadha V, Warady BA, Blowey DL, Simckes AM, Alon US (2000) Tenckhoff catheters prove superior to cook catheters in pediatric acute peritoneal dialysis. Am J Kidney Dis 35:1111–1116

    Article  PubMed  CAS  Google Scholar 

  12. Coulthard MG, Hey EN (1985) Effect of varying water intake on renal function in healthy preterm babies. Arch Dis Child 60:614–620

    Article  PubMed  CAS  Google Scholar 

  13. Coulthard MG, Sharp J (1995) Haemodialysis and ultrafiltration in babies weighing under 1000 g. Arch Dis Child 73:F162–F165

    Article  CAS  Google Scholar 

  14. Coulthard MG, Vernon B (1995) Managing acute renal failure in very low birthweight infants. Arch Dis Child 73:F187–F192

    Article  CAS  Google Scholar 

  15. Cozzolino DJ, Cendron M (1997) Bilateral renal vein thrombosis in a newborn: a case of prenatal renal vein thrombosis. Urology 50:128–131

    Article  PubMed  CAS  Google Scholar 

  16. Emery EF, Greenough A (1993) Efficacy of low-dose dopamine infusion. Acta Paediatr 82:430–432

    Article  PubMed  CAS  Google Scholar 

  17. Engle WD (1986) Evaluation of renal function and acute renal failure in the neonate. Pediatr Clin North Am 33:129–151

    PubMed  CAS  Google Scholar 

  18. Farnoux C, Camard O, Pinquier D, Hurtaud-Roux MF, Sebag G, Schlegel N, Beaufils F (1998) Recombinant tissue-type plasminogen activator therapy of thrombosis in 16 neonates. J Pediatr 133:137–140

    Article  PubMed  CAS  Google Scholar 

  19. Fuchshuber A, Niaudet P, Gribouval O, Jean G, Gubler MC, Broyer M, Antignac C (1996) Congenital nephrotic syndrome of the Finnish type: linkage to the locus in a non-Finnish population. Pediatr Nephrol 10:135–138

    PubMed  CAS  Google Scholar 

  20. Gemelli M, Manganaro R, Mami C, De Luca F (1990) Longitudinal study of blood pressure during the 1st year of life. Eur J Pediatr 149:318–320

    Article  PubMed  CAS  Google Scholar 

  21. Goble MM, Rocchini AP (1991) Neonatal hypertension. In: Donn SM, Faix RG (eds) Neonatal emergenices. Futura, Mount Kisco/NY, p 387

    Google Scholar 

  22. Goldman M, Lahat E, Strauss S, Reisler G, Livne A, Gordin L, Aladjem M (2000) Imaging after urinary tract infection in male neonates. Pediatrics 105:1232–1235

    Article  PubMed  CAS  Google Scholar 

  23. Gouyon JB, Guignard JP (2000) Management of acute renal failure in newborns. Pediatr Nephrol 14:1037–1044.

    Article  PubMed  CAS  Google Scholar 

  24. Guignard JP, John EG (1986) Renal function in the tiny premature infant. Clin Perinatol 13:377–401

    PubMed  CAS  Google Scholar 

  25. Heaton PA, Smales O, Wong W (1999) Congenital nephrotic syndrome responsive to Captopril and indometacin. Arch Dis Child 81:174–175

    Article  PubMed  CAS  Google Scholar 

  26. Hibbert J, Howlett DC, Greenwood KL, MacDonald LM, Saunders AJ (1997) The ultrasound appearances of neonatal renal vein thrombosis. Br J Radiol 70:1191–1194

    PubMed  CAS  Google Scholar 

  27. Holmberg C, Antikainen M, Ronnholm K, Ala Houhala M, Jalanko H (1995) Management of congenital nephrotic syndrome of the Finnish type. Pediatr Nephrol 9:87–93

    Article  PubMed  CAS  Google Scholar 

  28. International PHVD Drug Trial Group (1998) International randomised controlled trial of acetazolamide and furosemide in posthaemorrhagic ventricular dilatation in infancy. Lancet 352:433–440

    Article  Google Scholar 

  29. Karlowicz MG, Adelman RD (1992) Acute renal failure in the neonate. Clin Perinatol 19:139–158

    PubMed  CAS  Google Scholar 

  30. Kim MS, Stablein D, Harmon WE (1998) Renal transplantation in children with congenital nephrotic syndrome: a report of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS). Pediatr Transplant 2:305–308

    PubMed  CAS  Google Scholar 

  31. Klinge J, Scharf J, Rupprecht T, Boswald M, Hofbeck M (1998) Selective thrombolysis in a newborn with bilateral renal venous and cerebral thrombosis and heterozygous APC resistance. Nephrol Dial Transplant 13:3205–3207

    Article  PubMed  CAS  Google Scholar 

  32. Leititis JU, Burghard R, Gordjani N, Kaethner T, Brandis M (1987) Entwicklungsphysiologische Aspekte der Volumen- und Natriumregulation bei Frühgeborenen und reifen Neugeborenen. Monatsschr Kinderheilkd 135:3–9

    PubMed  CAS  Google Scholar 

  33. Libenson MH, Kaye EM, Rosman NP, Gilmore HE (1999) Acetazolamide and furosemide for posthemorrhagic hydrocephalus of the newborn. Pediatr Neurol 20:185–191

    Article  PubMed  CAS  Google Scholar 

  34. Nuss R, Hays T, Manco-Johnson M (1994) Efficacy and safety of heparin anticoagulation for neonatal renal vein thrombosis. Am J Pediatr Hematol Oncol 16:127–131

    PubMed  CAS  Google Scholar 

  35. Patrakka J, Kestila M, Wartiovaara J et al. (2000) Congenital nephrotic syndrome (NPHS1): features resulting from different mutations in Finnish patients. Kidney Int 58:972–980

    Article  PubMed  CAS  Google Scholar 

  36. Pohl M, Zimmerhackl LB, Heinen F, Sutor AH, Schneppenheim R, Brandis M (1998) Bilateral renal vein thrombosis and venous sinus thrombosis in a neonate with factor V mutation (FV Leiden). J Pediatr 132:159–161

    Article  PubMed  CAS  Google Scholar 

  37. Rasoulpour M, Marinelli KA (1992) Systemic hypertension. Clin Perinatol 19:121–137

    PubMed  CAS  Google Scholar 

  38. Report of the Second Task Force on Blood Pressure Control in Children (1987) Pediatrics 79:1–25

    Google Scholar 

  39. Rodriguez-Soriano J, Vallo A, Oliveros R, Castillo G (1983) Renal handling of sodium in premature and full-term neonates: a study using clearance methods during water diuresis. Pediatr Res 17:1013–1016

    Article  PubMed  CAS  Google Scholar 

  40. Savage JM, Jefferson JA, Maxwell AP, Hughes AE, Shanks JH, Gill D (1999) Improved prognosis for congenital nephrotic syndrome of the Finnish type in Irish families. Arch Dis Child 80:466–469

    Article  PubMed  CAS  Google Scholar 

  41. Seri I (1995) Cardiovascular, renal, and endocrine actions of dopamine in neonates and children. J Pediatr 126:333–344

    Article  PubMed  CAS  Google Scholar 

  42. Seri I, Rudas G, Bors Z, Kanyicska B, Tulassay T (1993) Effects of low-dose dopamine infusion on cardiovascular and renal functions, cerebral blood flow, and plasma catecholamine levels in sick preterm neonates. Pediatr Res 34:742–749

    Article  PubMed  CAS  Google Scholar 

  43. Sonntag J, Prankel B, Waltz S (1996) Serum creatinine concentration, urinary creatinine excretion and creatinine clearance during the first 9 weeks in preterm infants with a birth weight below 1500 g. Eur J Pediatr 155:815–819

    Article  PubMed  CAS  Google Scholar 

  44. de Swiet M, Fayers P, Shinebourne EA (1989) Systolic blood pressure in a population of infants in the first year of life: the Brompton study. Pediatrics 65:1028–1035

    Google Scholar 

  45. Toth-Heyn P, Drukker A, Guignard JP (2000) The stressed neonatal kidney: from pathophysiology to clinical management of neonatal vasomotor nephropathy. Pediatr Nephrol 14:227–239

    Article  PubMed  CAS  Google Scholar 

  46. Turner A, Haycock GB (1999) Renal function and renal failure in the newborn. In: Hansen TN, Mcintosh N (eds) Current topics in neonatology, Vol 3. WB Saunders, London, Edinburgh, New York, Philadelphia, Sydney, Toronto, pp 1–23

    Google Scholar 

  47. Warady BA, Beiden B, Kohaut E (1999) Neurodevelopmental outcome of children initiating peritoneal dialysis in early infancy. Pediatr Nephrol 13:759–765

    Article  PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2002 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Maier, R.F. (2002). Nierenkrankheiten. In: Bein, G., Maier, R.F., Waldschmidt, J. (eds) Neugeborenenintensivpflege. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-08937-8_13

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-08937-8_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-41360-8

  • Online ISBN: 978-3-662-08937-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics