• R. F. Maier


In der Neonatalperiode ist die Nierenfunktion im Vergleich zu älteren Kindern und Erwachsenen noch eingeschränkt (Tabelle 13–1). Bedingt durch einen hohen renalen Gefäßwiderstand sind während der Fetalzeit der renale Blutfluß und damit die glomeruläre Filtrationsrate (GFR) niedrig. Nach der Geburt sinkt der renale Gefäßwiderstand, renaler Blutfluß und GFR steigen in den ersten Lebensmonaten kontinuierlich an. Erwachsenenwerte werden mit etwa 18 Monaten erreicht. Da Kreatinin im Tubulus weder resorbiert noch sezerniert wird, stellt die Kreatininclearance ein Maß für die GFR dar (Tabelle 13–2).


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© Springer-Verlag Berlin Heidelberg 2002

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  • R. F. Maier

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