Abstract
In 1893 William Gowers concluded that “If the diagnosis of an intracranial aneurysm is certain, the prognosis is extremely grave” (1). This statement is unfortunately still valid.
“It is with a considerable degree of genuine humility that we broach the topic of cerebral vasospasm. This humility is the result of 20 years of disappointment, frustration, and bewilderment. The feeling of helplessness related to the relentness deterioration of a patient with this entity is matched only by that associated with the care of the victims of spinal cord injury. This is a feeling we have all shared and this has been the primary force driving all of us. It has literally compelled us to turn to the laboratory for answers, and there, in spite of heroic efforts, few revelations and no miracles have emerged.”
(Thoralf Sundt & Dudley Davis, The Mayo Clinic, 1979)
Part of this study was supported by grants from Greta and Johan Kocks Foundation and Thorsten and Elsa Segerfalks Foundation
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References
Gowers, W.R.: Intra-cranial aneurism. In: A manual of diseases of the nervous system. Vol. II, pp. 529–540. London: J. and A. Churchill 1893
Denny-Brown, D., Harvey Cushing: The man. J. Neurosurg. 50, 17–19 (1979)
Symonds, C.: Contributions to the clinical study of intracranial aneurysms. With Harvey Cushing. (Reprinted from Guy’s Hospital Reports, 1923 ) In: Studies in Neurology. pp. 27–47. London: Oxford University Press 1970
Dott, N.M.: Intracranial aneurysms: cerebral arterio-radiography: surgical treatment: Edinburgh Med. J. 40 (Section on Trans. Med-Chir. Soc. Edinburgh), 219–234 (1933)
Dandy, W.E.: Intracranial aneurysm of the internal carotid artery. Cured by operation. Annals of Surgery 107, 654–659 (1938)
Dandy, W.E.: Intracranial arterial aneurysms. New York and London: Hafner; Ithica, New York: Comstock Publishing Co. 1944 (reprinted 1969 )
Millikan, C.H.: Cerebral vasospasm and ruptured intracranial aneurysm. Arch. Neurol. 32, 433–449 (1975)
Norlén, G., Olivecrona, H.: The treatment of aneurysms of the circle of Willis. J. Neurosurg. 10, 404–415 (1953)
Bucy, P.C.: Editorial reply in Surg. Neurol. 14, 386 (1980)
Hamby, W.B.: Intracranial surgery for aneurysms. Progr. Neurol. Surg. 3, 1–65 (1969)
Pool, J.L.: New dimension in aneurysm surgery. Columbia Univ. Phys. Q 10, 18–20 (1965)
Yasargil, M.G., Fox, J.L.: The microsurgical approach to intracranial aneurysms. Surg. Neurol. 3, 7–14 (1975)
Yasargil, M.G., Fox, J.L., Ray, M.W.: The operative approach to aneurysms of the anterior communicating artery. In: Advances and technical standards in neurosurgery. VoL 2. Krayenbühl, H. (ed), pp. 113–170, New York, Wien: Springer 1974
Fox, J.L., Ablin, M.S., Bader, D.C.H. et al.: Microsurgical treatment of neurovascular disease. Neurosurgery 3, 285–337 (1978)
Kagström,E., Greitz, T., Hanson, J. et al.: Changes in cerebral blood flow after subarachnoid hemorrhages. In: Proceedings of the Third International Congress of Neurological Surgery, 1965. Excerpta Med. Int. Cong. Series 110, 629–633, Amsterdam 1966
Simeone, F.A., Trepper, P., Brown, D.: Cerebral blood flow evaluation of prolonged experimental cerebral vasospasm. J. Neurosurg. 37, 302–311 (1972)
Kapp, J., Mahaley, M.S. Jr., Odom, G.L.: Cerebral arterial spasm. Part 1: Evaluation of experimental variables affecting the diameter of the exposed basilar artery. J. Neurosurg. 29, 331–338 (1968)
Sundt, I.M., Davis, D.H.: Reactions of cerebrovascular smooth muscle to blood and ischemia: primary versus secondary vasospasm. In: Cerebral arterial spasm: Proceedings of the Second International Workshop. Wilkins, R.H. (ed), pp. 244–250. Baltimore: Williams and Wilkins Co. 1980
Mizukami, M., Kawase, T., Tazawa, T. et al.: Hypothesis and clinical evidence for the mechanism of chronic cerebral vasospasm after subarachnoid hemorrhage. In: Cerebral arterial spasm: Proceedings of the Second International Workshop. Wilkins, R.H. (ed.), pp. 97–106. Baltimore: Williams and Wilkins Co. 1980
Samson, D.S., Hodosh, R.M., Reid, W.R. et al.: Risk of intracranial aneurysm surgery in the good grade patient: early versus late operation. Neurosurgery 5, 442–426 (1979)
Sano, K., Saito, I.: Timing and indication for surgery for ruptured intracranial aneurysms with regard to cerebral vasospasm. Acta Neurochir. 41, 49–60 (1978)
Sundt, M., Jr.: Cerebral vasospasm following subarachnoid hemorrhage: evolution, management, and relationship to timing of surgery. Clin. Neurosurg. 24, 228–239 (1977)
Weir, B., Aronyk, K.: Management mortality and the timing of surgery for supratentorial aneurysms. J. Neurosurg. 54, 146–150 (1981)
Yasargil, M.G., Smith, R.D.: Surgery on the carotid system in the treatment of hemorrhagic stroke. In: Stroke. Advances in Neurology, Vol. 16. Thompson RA, Green JR (eds.), pp. 181–209. New York: Raven Press 1977
Yoshimoto, T., Uchida, K., Kaneko, T. et al.: An analysis of follow-up results of 1000 intracranial saccular aneurysms with definitive surgical treatment. J. Neurosurg. 50, 152–157 (1979)
Adams, H.P., Kassel, N.F., Torner, J.C. et al.: Early management of aneurysmal subarachnoid hemorrhage. A report of the Cooperative Aneurysm Study. J. Neurosurg. 54, 141–145 (1981)
Suzuki, J., Onuma, T., Yoshimoto, T.: Results of early operations on cerebral aneurysms. Surg. Neurol. 11, 407–412 (1979)
Boullin, D.J., Mohan, J., Grahame-Smith, D.G.: Evidence for the presence of a vasoactive substance (possibly involved in the aetiology of cerebral arterial spasm) in cerebrospinal fluid from patients with subarachnoid haemorrhage. J. NeuroL Neurosurg. Psychiat. 39, 756–766 (1976)
Sano, K., Saito, I.: Timing of microsurgical treatment of ruptured intracranial aneurysms. In: Cerebral arterial spasm: Proceedings of the Second International Workshop. Wilkins, R.H. (ed.), pp. 447–454. Baltimore: Williams and Wilkins Co. 1980
Alksne, J.F., Branson, P.J.: Pathogenesis of cerebral vasospasm. Neurol. Res. 2, 274–282 (1980)
Tanabe, Y., Sakata, K., Yamada, H. et al.: Cerebral vasospasm and ultrastructural changes in cerebral arterial wall. An experimental study. J. Neurosurg. 49, 229–238 (1978)
Asano, T., Tanishima, T., Sasaki, T. et al.: Possible participation of free radical reactions initiated by clot lysis in the pathogenesis of vasospasm after subarachnoid hemorrhage. In: Cerebral arterial spasm:Proceedings of the Second International Workshop. Wilkins, R.H. (ed.), pp. 190–201. Baltimore: Williams & Wilkins Co. 1980
Sano, K., Asano, T., Tanishima, T. et al.: Lipid peroxidation as a cause of cerebral vasospasm. Neurol. Res. 2, 253–271 (1980)
Sano, K., Sasaki, T., Asano, I.: Cerebral Vasospasm: The result of lipid peroxidation leading to inhibition of prostacyclin biosynthesis in the cerebral artery. Presented at the 50th Anniversary Meeting of the American Association of Neurological Surgeons in Boston 5/49/4 1981. In: Congress Scientific Manuscripts. ( Paper 52 )
Sasaki, T., Wakai, S., Asano, T. et al.: The effect of a lipid hydroperoxide of arachidonic acid on the canine basilar artery. An experimental study on cerebral vasospasm. J. Neurosurg. 54, 357–365 (1981)
Ljunggren, B., Brandt, L., Klgström, E., Sundbärg, G.: Results of early operations for ruptured aneurysms. J. Neurosurg. 54, 473–479 (1981)
Hunt, W.E., Hess, R.M.: Surgical risk as related to time of intervention in the repair of intracranial aneurysms. J. Neurosurg. 28, 14–19 (1968)
Saito, I., Ueda, Y., Sano, K.: Significance of vasospasm in the treatment of ruptured intracranial aneurysms. J. Neurosurg. 47, 412–429 (1977)
White, R.P.: Multiplex origins of cerebral vasospasm. In: Cerebrovascular diseases. Eleventh Princeton Conference. Price, T.R., Nelson, E. (eds.), pp. 307–319. New York: Raven Press 1979
Wilkins, R.H.: The role of intracranial arterial spasm in the timing of operations for aneurysm. Clin. Neurosurg. 29, 121–134 (1968)
Post, K.D., Flamm, E.S., Goodgold, A. et al.: Ruptured intracranial aneurysms. Case morbidity and mortality. J. Neurosurg. 46, 290–295 (1977)
Brandt, L., Ljunggren, B., Andersson, K.E., Hindfelt, B., Teasdale, G.: Vasoconstrictive effects of human posthemorrhagic cerebrospinal fluid on cat pial arterioles in situ. J. Neurosurg. 54, 351–356 (1981)
Brandt, L., Ljunggren, B., Andersson, K.E., Hindfelt, B.: Individual variations in response of human cerebral arterioles to vasoactive substances, human plasma, and cerebrospinal fluid from patients with aneurysmal subarachnoid hemorrhage. J. Neurosurg. 55, 431–437 (1981)
Boullin, D.J., Brandt, L., Ljunggren, B., Tagari, P.: Vasoconstrictor activity in cerebrospinal fluid from patients subjected to early surgery for ruptured intracranial aneurysms. J. Neurosurg. 55, 237–245 (1981)
Pickard, J.D., Tamura, A., Stewart, M. et al.: Prostacyclin, indomethacin and the cerebral circulation. Brain Res. 197, 425–431 (1980)
Boullin, D.J., Bunting, S., Blaso, W.P. et al.: Responses of human and baboon arteries to prostaglandin endoperoxides and biologically generated and synthetic prostacyclin: their relevance to cerebral arterial spasm in man. Br. J. Clin. Pharmacol. 7, 139–147 (1979)
Brandt, L., Ljunggren, B., Andersson, K.E., Hindfelt, B., Uski, T.: Effects of indomethacin and prostacyclin on isolated human pial arteries contracted by cerebrospinal fluid from patients with aneurysmal subarachnoid hemorrhage. J. Neurosurg. 55: 877–883 (1981)
Golenhofen, K., Hermstein, N.: Differentiation of calcium activation mechanisms in vascular smooth muscle by selective suppression with verapamil and D600. Blood vessels 12, 21–37 (1975)
Somlyo, A.V., Somlyo, A.P.: Electromechanical and pharmacomechanical coupling in vascular smooth muscle. J. Pharmacol. Exp. Ther. 159, 129–145 (1968)
Bolton, T.B.: Mechanisms of action of transmitters and other substances on smooth muscle. Physiol. Rev. 59, 606–718 (1979)
Fleckenstein, H.: Specific pharmacology of calcium in myocardium, cardiac pacemakers, and vascular smooth muscle. Ann. Rev. Pharmacol. Toxicol. 17, 149–166 (1977)
Church, J., Zsoter, T.: Calcium antagonistic drugs. Mechanisms of action. Can. J. Physiol. Pharmacol. 58, 254–264 (1980)
Brandt, L., Andersson, K.E., Edvinsson, L., Ljunggren, B.: Effects of extracellular calcium and calcium antagonists on contractile responses of human and mesenteric arteries. J. CBF and Meabolism 1, 339–347 (1981)
Brandt, L., Ljunggren, B., Andersson, K.E., MacKenzie, E.T., Tamura, A., Teasdale, G.: Effects on feline cortical pial microvasculature of topical application of a calcium antagonist (Nifedipine) under normal conditions and in focal ischemia. J. CBF and Metabolism (in press)
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Brandt, L., Ljunggren, B., Andersson, KE., Hindfelt, B. (1982). Studies on Cerebral Vasospasm. In: Brock, M. (eds) Modern Neurosurgery 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-08801-2_44
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