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Immunohistochemical Classification of Pituitary Adenomas

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Book cover Modern Neurosurgery 1

Abstract

At the beginning of this century, Benda (1) and Erdheim (7) classified the anterior pituitary cells into eosinophilic, basophilic and chromophobic types according to the staining affinity of the cytoplasm. This classification was also applied to the pituitary adenomas, and for a long time it was considered to correlate with the endocrinological functions of adenomas. On the other hand, it was known that the classification could not always correspond to the hormonal functions; i.e., acromegaly or Cushing’s disease were sometimes associated with chromophobe adenomas. Since the latter half of 1960, when the radioimmunoassay for anterior pituitary hormones was available, various kinds of functioning adenomas have been diagnosed endocrinologically. Moreover several cases of multihormonal adenomas were reported in the literature.

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Authors
  1. A. Teramoto
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  2. T. Fukushima
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  3. K. Takakura
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  4. K. Sano
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  5. R. Y. Osamura
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Editors and Affiliations

  1. Abteilung für Neurochirurgie Neurochirurgische/Neurologische Klinik und Poliklinik, Universitätsklinikum Steglitz, Freie Universität Berlin, Hindenburgdamm 30, D-1000, Berlin 45, Germany

    Mario Brock

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© 1982 Springer-Verlag Berlin Heidelberg

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Teramoto, A., Fukushima, T., Takakura, K., Sano, K., Osamura, R.Y. (1982). Immunohistochemical Classification of Pituitary Adenomas. In: Brock, M. (eds) Modern Neurosurgery 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-08801-2_19

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  • DOI: https://doi.org/10.1007/978-3-662-08801-2_19

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-08803-6

  • Online ISBN: 978-3-662-08801-2

  • eBook Packages: Springer Book Archive

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