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Medicinal and Aromatic Plants XII pp 118–136Cite as

Production of Quinolizidine Alkaloids in in Vitro Cultures of Legumes

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Part of the book series: Biotechnology in Agriculture and Forestry ((AGRICULTURE,volume 51))

Abstract

Quinolizidine alkaloids (QA), of which more than 170 structures have been reported (overviews in: Mears and Mabry 1971; Kinghorn and Balandrin 1984; Salatino and Gottlieb 1980; Wink 1993), are distinct from other alkaloids in that they contain at least one quinolizidine ring system. According to the degree of substitution at least seven different groups can be distinguished: (1) the lupinine-type, (2) the Leontidine-type, (3) the sparteine/lupanine/ multiflorine-type, (4) the alpha-pyridone-type, (5) the matrine-type, (6) the Ormosia-type, and (7) piperidine and dipiperidines, which often occur together with QA (Fig. 1).

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  1. Institute for Pharmaceutical Biology, University of Heidelberg, Im Neuenheimer Feld 364, 69120, Heidelberg, Germany

    Michael Wink

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  1. Michael Wink
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  1. Graduate School of Science, Department of Biological Sciences, University of Tokyo, 7-3-1 Hongo, 113-0033, Bunkyo-ku, Tokyo, Japan

    Toshiyuki Nagata

  2. Graduate School of Pharmaceutical Sciences, University of Tokyo, 7-3-1 Hongo, 113-0033, Bunkyo-ku, Tokyo, Japan

    Yutaka Ebizuka

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Wink, M. (2002). Production of Quinolizidine Alkaloids in in Vitro Cultures of Legumes. In: Nagata, T., Ebizuka, Y. (eds) Medicinal and Aromatic Plants XII. Biotechnology in Agriculture and Forestry, vol 51. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-08616-2_7

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  • DOI: https://doi.org/10.1007/978-3-662-08616-2_7

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