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Genetic Pathways to Human Cancer

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Mechanisms in Carcinogenesis and Cancer Prevention

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 156))

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Abstract

Carcinogenesis is a multi-step process and it is generally accepted that morphological changes that occur in malignant progression reflect the sequential acquisition of genetic alterations. Sequences of genetic alterations appear to be tissue- and cell type-specific. In this chapter, we summarize and discuss genetic pathways leading to brain tumors, stomach cancer, and lung cancer.

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Authors
  1. H. Ohgaki
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  2. W. Yasui
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  3. J. Yokota
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Editors and Affiliations

  1. Unit of Chemoprevention, International Agency for Research on Cancer, 150, cours Albert-Thomas, 69372, Lyon, France

    Harri U. Vainio

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© 2003 Springer-Verlag Berlin Heidelberg

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Ohgaki, H., Yasui, W., Yokota, J. (2003). Genetic Pathways to Human Cancer. In: Vainio, H.U., Hietanen, E.K. (eds) Mechanisms in Carcinogenesis and Cancer Prevention. Handbook of Experimental Pharmacology, vol 156. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-08602-5_3

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  • DOI: https://doi.org/10.1007/978-3-662-08602-5_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-07859-0

  • Online ISBN: 978-3-662-08602-5

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