Adjuvante systemische Therapie

  • V. Möbus
  • T. Volm
  • R. Kreienberg
Part of the Onkologie Aktuell book series (ONKAKTUELL)


Eine größere Anzahl von einzelnen Studien, insbesondere aber die Metaanalyse der „Early Breast Cancer Trialist’s Collaborative Group“ (EB-CTCG), haben den Nutzen einer Chemo- und Hormontherapie in der adjuvanten Behandlung des Mammakarzinomes eindrucksvoll bewiesen. Die letzte publizierte Metaanalyse datiert aus dem Jahre 1998 (Early Breast Cancer Trialists’ Collaborative Group 1998a, b). Ihre Ergebnisse haben einen Paradigmenwechsel in der Therapie eingeleitet. Während bis dato das Alter der Patientin (Prä- vs. Postmenopause) die Hauptdiskriminante der Therapieentscheidung war (Chemo- vs. Hormontherapie), ist diese durch den Nachweis der Expression des Steroidrezeptors ersetzt worden.


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© Springer-Verlag Berlin Heidelberg 2002

Authors and Affiliations

  • V. Möbus
  • T. Volm
  • R. Kreienberg

There are no affiliations available

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