Hypothesis Testing and the Choice of the Dose-Response Model

  • Christian Streffer
  • H. Bolt
  • D. Føllesdal
  • P. Hall
  • J. G. Hengstler
  • P. Jakob
  • D. Oughton
  • K. Prieß
  • E. Rehbinder
  • E. Swaton
Part of the Wissenschaftsethik und Technikfolgenbeurteilung book series (ETHICSSCI, volume 23)


Scientists have been debating the shape of dose-response curves for ionising radiation since exposures were found to be harmful to health. The initial assumption was that there was a threshold to the appearance of a health detriment, including cancer. But developments in the knowledge and aetiology of cancer led toxicologists to first suggest a non-threshold model during the early 1960s (Roderick 1992). Since that time a number of models have been suggested, and present work in health physics, toxicology and epidemiology is concerned with questions about both the shape of the dose-response curve and whether or not a threshold exists.


Radiation Protection Radiological Protection Atomic Bomb Survivor Biological Endpoint Atmospheric Nuclear Weapon Test 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2004

Authors and Affiliations

  • Christian Streffer
    • 1
  • H. Bolt
  • D. Føllesdal
  • P. Hall
  • J. G. Hengstler
  • P. Jakob
  • D. Oughton
  • K. Prieß
  • E. Rehbinder
  • E. Swaton
  1. 1.EssenGermany

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