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Das Körpergewicht im Rahmen der Schizophrenie unter besonderer Berücksichtigung der clozapin-induzierten Gewichtszunahme und dem damit einhergehenden Anstieg der Leptinsekretion

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Leponex

Zusammenfassung

Gewichtszunahmen unter neuroleptischer Medikation sind jedem Kliniker bekannt. Mit der Erhebung einer Gewichtsanamnese und der epidemiologischen Einordnung eines gemessenen Körpergewichts bei schizophrenen Patienten sind die behandelnden Ärzte jedoch bislang wenig vertraut. Die Veränderungen vollziehen sich im Verlauf von längeren Zeitabschnitten, so daß sie im Rahmen von kurzen stationären Behandlungen kaum bemerkt werden. Eine registrierte Gewichtszunahme von einigen Kilogramm wird vielfach als „harmlose“ Nebenwirkung der Pharmakotherapie billigend in Kauf genommen. Einige Monate später kann die Gewichtszunahme 20 Kilogramm und mehr betragen. Der Patient ist dann einer psychosozialen Doppelbelastung ausgesetzt; neben der Stigmatisierung durch die Schizophrenie kommt die einer Adipositas hinzu.

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Authors
  1. T. Brömel
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  2. A. Hinney
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  3. E. Schulz
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  4. F. Theisen
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  5. H. Remschmidt
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  6. H.-Ch. Krieg
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  7. J. Hebebrand
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Editor information

Editors and Affiliations

  1. Psychiatrische und Nervenklinik, Univ.-Krankenhaus Eppendorf, Martinistraße 52, D-20246, Hamburg, Deutschland

    D. Naber

  2. Psychiatrische Universitätsklinik, Wilhelm-Klein-Straße 27, CH-4025, Basel, Switzerland

    F. Müller-Spahn

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© 1999 Springer-Verlag Berlin Heidelberg

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Brömel, T. et al. (1999). Das Körpergewicht im Rahmen der Schizophrenie unter besonderer Berücksichtigung der clozapin-induzierten Gewichtszunahme und dem damit einhergehenden Anstieg der Leptinsekretion. In: Naber, D., Müller-Spahn, F. (eds) Leponex. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-08362-8_7

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  • DOI: https://doi.org/10.1007/978-3-662-08362-8_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-64707-2

  • Online ISBN: 978-3-662-08362-8

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