Zusammenfassung
Das Phänomen des physiologischen Deszensus, Spezifikum des Menschen und der Säuger, wurde bereits 1841 erkannt [15]. Das Phänomen des Maldeszensus läßt sich nur verstehen aus der Ableitung von der Normalität. Die Mesonephros-Formation erscheint in der 4. Schwangerschaftswoche als paariger Wulst an der dorsalen Bauchwand. Zusammen mit primitiven Sexualsträngen entstehen in der 5. SSW der Müller- und der Wolff-Gang. Die Keimdrüsen sind zu diesem Zeitpunkt noch undifferenziert. Das vom Y-Chromosom determinierte HY-Antigen führt dann in der 7. SSW zum Beginn der Ausdifferenzierung einer männlichen Gonade. Aus dem Wolff-Gang entwickeln sich Epididymis, Ductus deferens und die Vesiculae seminales, während der in den fetalen Sertoli-Zellen gebildete Anti-Müller-Faktor die Müller-Gänge zum Utriculus prostaticus zurückbildet. Der Deszensus des Hodens verläuft von dorsokranial nach ventrokaudal. Anfänglich rund gestaltet, nimmt der Hoden zur Passage durch den Leistenkanal seine spätere ovaläre Form an. In dieser Phase umklammert ihn der rasch wachsende Nebenhoden.
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Rösch, W., Sigel, A., Kühn, R. (1993). Benigne testikuläre Fehlbildungen und Erkrankungen des Kindesalters. In: Sigel, A. (eds) Kinderurologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-08082-5_25
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