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Das Kind mit intersexuellem Genitale

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Kinderurologie

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Zusammenfassung

Nach A. Jost [11], der 1972 die grundsätzlichen Mechanismen der sexuellen Differenzierung aufklärte, werden ein chromosomales, ein gonadales und ein äußeres, phänotypisches Geschlecht unterschieden.

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Literatur

  1. Aarskog D (1971) Intersex conditions masquerading as hypospadias. Birth Defects 7:122

    PubMed  CAS  Google Scholar 

  2. Bongiovanni AM (1961) Unusual steroid pattern in congenital adrenal hyperpla-sia: deficiency of 3β-hydroxydehydrogenase. J Clin Endocrinol Metab 21:860

    Article  CAS  Google Scholar 

  3. Bongiovanni AM, Eberlein WR, Goldman AS, New M (1967) Disorders of adrenal steroid biogenesis. Recent Prog Horm Res 23:375

    PubMed  CAS  Google Scholar 

  4. Brook CGD (1981) Persistent Müllerian duct syndrome. In: Josso N (ed) The intersex child. Karger, Basel, p 100

    Google Scholar 

  5. Davidoff F, Federman DD (1973) Mixed gonadal dysgenesis. Pediatrics 52:727

    Google Scholar 

  6. Forest MG, Sizonenko PC, Cathiard AM, Bertrand J (1974) Hypophyso-gonadal function in humans during the first year of life: evidence for testicular activity in early infancy. J Clin Invest 53:819

    Article  PubMed  CAS  Google Scholar 

  7. Grumbach MM, Ducharme JR (1960) The effects of androgens on fetal sexual development, androgen-induced fenale pseudohermaphroditism. Fertil Steril 11:157

    PubMed  CAS  Google Scholar 

  8. Heremans GFP, Moolenaar AJ, Van Gelderen HH (1976) Female phenotype in a male child due to 17 alpha-hydroxylase deficiency. Arch Dis Child 51:721

    Article  PubMed  CAS  Google Scholar 

  9. Jeffcoate SL, Brooks RV, Prunty FT (1968) Secretion of androgens and estrogens in testicular feminization: studies in vivo and in vitro in two cases. Br Med J 1:208

    Article  PubMed  CAS  Google Scholar 

  10. Josso N, Picard JY, Tran D (1977) The antimüllerian hormone. Recent Prog Horm Res 33:117

    Google Scholar 

  11. Jost A (1972) A new look at the mechanism controlling sex differentiation in mammals. Johns Hopk Med J 130:38

    CAS  Google Scholar 

  12. Morris J (1953) The syndrome of testicular feminization in male pseudohermaphrodites. Am J Obstet Gynecol 65:1192

    PubMed  CAS  Google Scholar 

  13. Müller J (1984) Morphometry and histology of gonads from twelve children and adolescents with the androgen intensitivity (testicular feminization) syndrome. J Clin Endocrinol Metab 59:785

    Article  PubMed  Google Scholar 

  14. Mürset G, Zachmann M, Prader A, Fischer J, Labhart A (1970) Male external genitalia of a girl caused by a virilizing adrenal tumour of the mother. Acta Endocrinol 65:627

    PubMed  Google Scholar 

  15. O’Rahilly A (1977) The development of the vagina in the human. Birth Def 13:123

    Google Scholar 

  16. Ohno S, Nagay I, Ciccarese S, Iwata H (1979) Testis organizing H-Y Antigen and primary sex-determinizing mechanism of mammals. Recent Progr Horm Res 35:449

    PubMed  CAS  Google Scholar 

  17. Page DC (1986) Sex reversal Deletion mapping the male-determining function of the human Y chromosome. Cold Spring Harbor Symp Quant Biol 51:229

    Article  PubMed  CAS  Google Scholar 

  18. Peterson RE, Imperato-McGinley J, Gautier T, Sturla E (1977) Male pseudoher-maphroditism due to steroid 5 alpha-reductase deficiency. Am J Med 62:170

    Article  PubMed  CAS  Google Scholar 

  19. Pich G (1937) Über den angeborenen Eierstockmangel. Beitr Pathol Anat allg Pathol 98:218

    Google Scholar 

  20. Prader A (1986) Disorders of sexual differentiation (Intersexuality). In: Labhart A (ed) Clinical endocrinology. Theory and practice, 2nd edn. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  21. Saenger P, Goldman AS, Levine LS, Korth-Schutz S, Muecke FC, Katsumata M, Doberne Y, New MI (1978) Prepubertal diagnosis of steroid 5 alpha-reductase deficiency. J Clin Endocrinol Metab 46:627

    Article  PubMed  CAS  Google Scholar 

  22. Siiteri PK, Wilson JD (1974) Testosterone formation and metabolism during male sexual differentiation in the human embryo. J Clin Endocrinol 38:113

    Article  CAS  Google Scholar 

  23. Simpson E, Chandler P, Goulmy E, Disteche CM, Ferguson-Smith AM, Page DC (1987) Separation of the genetic loci for the H-Y antigen and for testis determination on human y chromosome. Nature 326:876

    Article  PubMed  CAS  Google Scholar 

  24. Sloan AR, Walsh PC (1976) Familial persistent Müllerian duct syndrome. J Urol 155:459

    Google Scholar 

  25. Sohval AR (1963) „Mixed“ gonadal dysgenesis: a variety of hermaphroditism. Am J Hum Genet 15:155

    PubMed  CAS  Google Scholar 

  26. Summit RL (1979) Genetic forms of hypogonadism in the male. Prog Med Genet 3:1

    Article  Google Scholar 

  27. Verhoeven ATM, Mastboom JL, van Leusden H, Velden WHM (1973) Virilization in pregnancy coexisting with an (ovarian) mucinous cystadenoma. A case report and review of virilizing ovarian tumors in pregnancy. Obstet Gynecol Surv 28:597

    Article  PubMed  CAS  Google Scholar 

  28. Wilkins L, Jones HW jr, Holman GH, Stempfei RS (1958) Masculinization of female fetus associated with administration of oral and intramuscular progestins during gestation. Non-adrenal female pseudohermaphroditism. J Clin Endocrinol Metab 18:559

    Article  PubMed  CAS  Google Scholar 

  29. Zäh W, Kalderon AE, Tucci JR (1975) Mixed gonadal dysgenesis. Acta Endocrinol (Suppl) 197:3

    Google Scholar 

Literatur

  1. Altwein JE (1990) Feminisierungsoperation bei Pseudohermaphroditismus femi-ninus. Akt Urol 21:1–10

    Google Scholar 

  2. Azziz R, Mulaikal RM, Migeon CJ, Jones HW jr, Rock JA (1986) Congenital adrenal hyperplasia: long term results following vaginal reconstruction. Fertil Steril 46:1011–1014

    PubMed  CAS  Google Scholar 

  3. Bolkenius M, Daum R, Roth H (1982) Korrekturoperationen am intersexuellen kindlichen Genitale — Indikation, Operationsverfahren, Zeitpunkt. Z Kinderchir 35:73–80

    PubMed  CAS  Google Scholar 

  4. Borgwardt G, Gdanietz K (1984) Results after operative correction of virilized female genitalia in children with congenital adrenal hyperplasia. Z Kinderchir 39:55–58

    PubMed  CAS  Google Scholar 

  5. Cukier J (1990) Ambiguités sexuelles. Masson, Paris

    Google Scholar 

  6. Dewhurst J, Grant DB (1984) Intersex problems. Arch Dis Child 59:1191–1194

    Article  PubMed  CAS  Google Scholar 

  7. Donahoe PK, Hendren WH (1984) Perineal reconstruction in ambiguous genitalia infants raised as females. Ann Surg 200:363–371

    Article  PubMed  CAS  Google Scholar 

  8. Donahoe PK, Crawford JD, Hendren WH (1979) Mixed gonadal dysgenesis, pathogenesis and management. J Pediatr Surg 14:287–300

    Article  PubMed  CAS  Google Scholar 

  9. Eickenberg HU, Mellin P, Walz KA, Ringert RH (1981) Evaluation and management of the child with ambiguous genitalia. Monogr Paediat 12:55–61

    CAS  Google Scholar 

  10. Federman DD (1987) Psychosexual adjustment in congenital adrenal hyperplasia. NEngl J Med 316:209–211

    Article  CAS  Google Scholar 

  11. Fortunoff St, Lattimer JK, Edson M (1964) Vaginoplasty technique for female pseudohermaphrodites. Surg Gynecol Obstet 118:545–548

    PubMed  CAS  Google Scholar 

  12. Glassberg KI (1987) Intersex disorders: Classification and management. In: Retik AB, Cukier J (eds) Pediatric urology. Williams & Wilkins, Baltimore, pp 330–351

    Google Scholar 

  13. Hecker WCh (1985) Operative Korrekturen des intersexuellen und des fehlgebildeten weiblichen Genitales. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  14. Hendren WH, Crawford JD (1969) Adrenogenital Syndrome: The anatomy of the anomaly and it’s repair. J Pediatr Surg 4:49–58

    Article  PubMed  CAS  Google Scholar 

  15. Jones HW jr (1977) Intersexes-surgical correction. Birth Defects 13:137–145

    PubMed  Google Scholar 

  16. Kumar H, Kiefer JH, Rosenthal IM, Clark SS (1974) Clitoroplasty: experience during a 19 year period. J Urol 111:81–84

    PubMed  CAS  Google Scholar 

  17. Lattimer JK (1961) Relocation and recession of the enlarged clitoris with preservation of the glas: An alternative to amputation. J Urol 86:113–116

    PubMed  CAS  Google Scholar 

  18. Lobe TE, Woodall DL, Richards GE, Cavallo A, Meyer WJ (1987) The complications of surgery for intersex: Changing patterns over two decades. J Pediatr Surg 22:651–652

    Article  PubMed  CAS  Google Scholar 

  19. Passerini-Glazel G (1989) A new 1-stage procedure for clitorovaginoplasty in severely masculinized female pseudohermaphrodites. J Urol 142:565–568

    PubMed  CAS  Google Scholar 

  20. Praetorius M (1981) Zur Korrektur des AGS-Genitales bei stärkeren Virilisie-rungsformen. Z Kinderchir 33:343–349

    PubMed  CAS  Google Scholar 

  21. Ringert RH, Walz KA (1985) Ergebnisse operativer Therapie der virilisierenden Vulva. Akt Urol 16:229–234

    Article  Google Scholar 

  22. Sharp RJ, Holder TM, Howard CP, Grunt JA (1987) Neonatal genital reconstruction. J Pediatr Surg 22:168–171

    Article  PubMed  CAS  Google Scholar 

  23. Snyder HMC (1988) Management of ambiguous genitalia in neonates. In: King LR (ed) Urologic surgery in neonates and young infants. Saunders, Philadelphia London Toronto, pp 346–385

    Google Scholar 

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Authors
  1. H. Böhles
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  2. R. H. Ringert
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Editors and Affiliations

  1. Urologischen Klinik und Poliklinik, Universität Erlangen-Nürnberg, Maximiliansplatz, W-8520, Erlangen, Bundesrepublik Deutschland

    Alfred Sigel (ehemal. Direktor) (ehemal. Direktor)

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© 1993 Springer-Verlag Berlin Heidelberg

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Böhles, H., Ringert, R.H. (1993). Das Kind mit intersexuellem Genitale. In: Sigel, A. (eds) Kinderurologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-08082-5_23

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  • DOI: https://doi.org/10.1007/978-3-662-08082-5_23

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-08083-2

  • Online ISBN: 978-3-662-08082-5

  • eBook Packages: Springer Book Archive

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