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Anästhetika

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Book cover Kinderanästhesie

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Zusammenfassung

Die meisten Medikamente werden bei Kindern aller Altersgruppen eingesetzt, obwohl die wissenschaftlichen Informationen unvollständig sind und Restriktionen von Hersteller- oder behördlicher Seite bestehen. Allerdings ist darauf zu achten, dass v. a. bei Neugeborenen und kranken Patienten große Variationen in der Pharmakokinetik und der Pharmakodynamik bestehen.

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Literatur

  • Adams HA, Werner C (1997) Vom Razemat zum Eutomer: (S)-Ketamin, Renaissance einer Substanz? Anästhesist 46:1026–1042

    Article  CAS  Google Scholar 

  • Bacher A, Burton AW, Uchida T, Zornow MH (1997) Sevoflurane or halothane anesthesia: can we tell the difference? Anesth Analg 85:1203–1206

    PubMed  CAS  Google Scholar 

  • Bailey JM (1997) Context-sensitive half-times and other decrement times of inhaled anesthetics. Anesth Analg 85: 681–686

    PubMed  CAS  Google Scholar 

  • Bevan JC, Donati F, Bevan DR (1986) Prolonged infusion of suxamethonium in infants and children. Br J Anaesth 58: 839–843

    Article  PubMed  CAS  Google Scholar 

  • Borgeat A, Wilder-Smith OHG, Suter PM (1994) The nonhyp-notic therapeutic applications of propofol. Anesthesiology 80:642–656

    Article  PubMed  CAS  Google Scholar 

  • Brandom BW, Brandom RB, Cook DR (1983) Uptake and distribution of halothane in infants: In vivo measurements and computer simulations. Anesth Analg 62:404–410

    PubMed  CAS  Google Scholar 

  • Cameron CB, Robinson S, Gregory GA (1984) The minimum alveolar concentration of isoflurane in children. Anesth Analg 63:418–422

    PubMed  CAS  Google Scholar 

  • Deer TR, Rich GF (1992) Propofol tolerance in a pediatric patient. Anesthesiology 77:828–829

    Article  PubMed  CAS  Google Scholar 

  • Fisher DM, Zwass MS (1992) MAC of desflurane in 60% nitrous oxide in infants and children. Anesthesiology 76: 354–356

    Article  PubMed  CAS  Google Scholar 

  • Förster H (1999) Das Soda-lime Problem. Anästhesist 48: 409–416

    Article  Google Scholar 

  • Fuchs-Buder T (1997) Neue Muskelrelaxanzien. Anästhesist 46:350–359

    Article  CAS  Google Scholar 

  • Gauntlett IS, Fisher DM, Hertzka RE et al. (1988) Pharmakokinetics of fentanyl in neonatal humans and lambs: effect of age. Anesthesiology 69:683–687

    Article  PubMed  CAS  Google Scholar 

  • Goudsouzian NG (1997) Mivacurium in infants and children. Paediatr Anesth 7:183–190

    Article  CAS  Google Scholar 

  • Gregory GA, Eger El, Munson ES (1969) The relationship between age and halothane requirement in man. Anesthesiology 30:488–491

    Article  PubMed  CAS  Google Scholar 

  • Hannallah RS, Baker SB, Casey W et al. (1991) Propofol: effective dose and induction characteristics in unpremedicated children. Anesthesiology 74: 217–219

    Article  PubMed  CAS  Google Scholar 

  • Hertzka RE, Gauntlett IS, Fisher DM et al. (1989) Fentanyl-induced ventilatory depression: effects of age. Anesthesiology 70:213–218

    Article  PubMed  CAS  Google Scholar 

  • Hobbhahn J, Funk W (1996) Sevofluran in der Kinderanästhesie. Anästhesist 45 (Suppl 1): S22–S27

    Article  Google Scholar 

  • Jöhr M (1999) Exzitation nach Sevofluran: Ein Problem in der Kinderanästhesie? Anästhesist 48:917–918

    Article  Google Scholar 

  • Kataria B, Epstein R, Bailey A et al. (1996) A comparison of sevoflurance to halothane in paediatric surgical patients: results of a multicentre international study. Paediatr Anaesth 6: 283–92

    Article  PubMed  CAS  Google Scholar 

  • Kearns GL, Abdel-Rahman SM, Alander SW et al. (2003) Developmental pharmacology-drug disposition, action, andtherapy in infants and children. N Engl J Med 349:1157–67

    Article  PubMed  CAS  Google Scholar 

  • Kern C, Erb T, Frei FJ (1997) Haemodynamic responses to sevoflurane compared with halothane during inhalational induction in children. Paediatr Anaesth 7/6:439–444

    Article  PubMed  CAS  Google Scholar 

  • Kobayashi S, Bito H, Obata Y et al. (2003) Compound A concentration in the circle absorber system during low-flow sevoflurane anesthesia: comparison of Dragersorb Free, Amsorb and Sodasorb II. J Clin Anesth 15/1:33–37

    Article  PubMed  CAS  Google Scholar 

  • LeDez KM, Lerman J (1987) The minimum alveolar concentration (MAC) of isoflurane in preterm neonates. Anesthesiology 67: 301–307

    Article  PubMed  CAS  Google Scholar 

  • Lerman J, Robinson S, Willis MM et al. (1983) Anesthetic requirement for halothane in young children 0–1 months and 1 – 6 months of age. Anesthesiology 59:421–424

    Article  PubMed  CAS  Google Scholar 

  • Lerman J, Gregory GA, Willis MM et al. (1984) Age and solubility of volatile anesthetics in blood. Anesthesiology 61: 139–143

    Article  PubMed  CAS  Google Scholar 

  • Levine MF, Spahr-Schopfer IA, Hartley E et al. (1993) Oral midazolam premedication in children: The minimum time interval for separation from parents. Can J Anaesth 40: 726–729

    Article  PubMed  CAS  Google Scholar 

  • Lynn AM, Nespeca MK, Opheim KE et al. (1993) Respiratory effects of intravenous morphine infusions in neonates, infants and children after cardiac surgery. Anesth Analg 77: 695 – 701

    Article  PubMed  CAS  Google Scholar 

  • Malinovsky JM, Lejus C, Servin F et al. (1993) Plasma concentrations of midazolam after i.V., nasal or rectal administration in children. Br J Anaesth 70: 617–620

    Article  PubMed  CAS  Google Scholar 

  • Marsh DF, Hatch DJ, Fitzgerald M (1997) Opioid systems and the newborn. Br J Anesth 79:787–795

    Article  CAS  Google Scholar 

  • McNeely JK, Buczulinski B, Rosner DR (2000) Severe neurological impairment in an infant after nitrous oxide anesthesia. Anesthesiology 93:1549–1550

    Article  PubMed  CAS  Google Scholar 

  • Meakin GH (2001) Recent advances in myorelaxant therapy. Paediatr Anaesth 11: 523–531

    Article  PubMed  CAS  Google Scholar 

  • Meakin GH, Pronske EH, Lerman J, Orr R, Joffe D, Savaree AM, Lynn AM (2001) Bronchospasm after rapacuronium in infants and children. Anesthesiology 94:926–927

    Article  PubMed  CAS  Google Scholar 

  • Murray D, Vandewalker G, Matherne P et al. (1987) Pulsed doppler and two-dimensional echocardiography: comparison of halothane and isoflurane on cardiac function in infants and small children. Anesthesiology 67:211 – 217

    Article  PubMed  CAS  Google Scholar 

  • Parke TJ, Stevens JE, Rice ASC et al. (1992) Metabolic acidosis and fatal myocardial failure after propofol infusion in children: five case reports. Br Med J 305:613 – 616

    Article  CAS  Google Scholar 

  • Payne K, Mattheyse FJ, Liebenberg D et al. (1989) The pharmacokinetics of midazolam in paediatric patients. Eur J Clin Pharmacol 37: 267–272

    Article  PubMed  CAS  Google Scholar 

  • Picard P, Tramer MR (2000) Prevention of pain on injection with propofol: a quantitative systematic review. Anesth Analg 90:963–969

    Article  PubMed  CAS  Google Scholar 

  • Piotrowski R, Petrow N (1990) Narkoseeinleitung bei Kindern: Propofol im Vergleich zu Thiopental nach der Prämedikation mit Midazolam. Anästhesist 39:398–405

    CAS  Google Scholar 

  • Ross AK, Davis PJ, Dear Gd GL, et al. (2001) Pharmacokinetics of remifentanil in anesthetized pediatric patients undergoing elective surgery or diagnostic procedures. Anest Analg 93:1393–1401

    Article  CAS  Google Scholar 

  • Saint-Maurice C, Meistelman C, Rey E et al. (1986) The pharmacokinetics of rectal midazolam for premedication in children. Anesthesiology 65:536–538

    Article  PubMed  CAS  Google Scholar 

  • Salanitre E, Rackow H (1969) The pulmonary exchange of nitrous oxide and halothane in infants and children. Anesthesiology 30:388–394

    Article  PubMed  CAS  Google Scholar 

  • Sammartino M, Bocci MG, Ferro G et al. (2003) Efficacy and safety of continuous intravenous infusion of remifentanil in preterm infants undergoing laser therapy in retinopathy of prematurity: clinical experience. Paediatr Anaesth 13:596–602

    Article  PubMed  CAS  Google Scholar 

  • Schulte-Sasse U, Eberlein HJ, Schmucker I et al. (1993) Sollte die Verwendung von Succinylcholin in der Kinderanästhesie neu überdacht werden? Anästhesiol Reanim 18:13–19

    CAS  Google Scholar 

  • Selzer RR, Rosenblatt DS, Laxova R, Hogan K (2003) Adverse effect of nitrous oxide in a child with 5,10-methylenetetrahy-drofolate reductase deficiency. N Engl J Med 349:45–50

    Article  PubMed  Google Scholar 

  • Sparr HJ, Jöhr M: Klinische Pharmakologie: Succinylcholin-Up-date (2002) Anästhesist 51: 565–575

    Article  CAS  Google Scholar 

  • Stevens WC, Dolan WM, Gibbons RT et al. (1975) Minimum alveolar concentrations (MAC) of isoflurane with and without nitrous oxide in patients of various ages. Anesthesiology 42:197–200

    Article  PubMed  CAS  Google Scholar 

  • Strauss JM, Baum J, Sumpelmann R et al. (1996) Zersetzung von Halothan, Enfluran und Isofluran an trockenem Atemkalk zu Kohlenmonoxid. Anästhesist 45: 798–801

    Article  CAS  Google Scholar 

  • Tramer MR (1997) Propofol and bradycardia: causation, frequency and severity. Br J Anaesth 78:642–651

    Article  PubMed  CAS  Google Scholar 

  • Uezono S, Goto T, Terui K, Ichinose F, Ishguro Y, Nakata Y, Monta S (2000) Emergence agitation after sevoflurane vs. propofol in pediatric patients. Anesth Analg 91:563–566

    Article  PubMed  CAS  Google Scholar 

  • Valley RD, Freid EB, Bailey AG, Kopp VJ, Georges LS, Fletcher J, Keifer A. (2003) Tracheal extubation of deeply anesthetized pediatric patients: a comparison of desflurane and sevoflurane. Anesth Analg 96:1320–1324

    Article  PubMed  CAS  Google Scholar 

  • Vasile B, Rasulo F, Candiani A, Latronico N. (2003) The pathophysiology of propofol infusion syndrome: a simple name for a complex syndrome. Intensive Care Med 29: 1417–1425

    Article  PubMed  Google Scholar 

  • Westrin P, Jonmarker C, Werner O (1989) Thiopental requirements for induction of anesthesia in neonates and in infants one to six months of age. Anesthesiology 71: 344–346

    Article  PubMed  CAS  Google Scholar 

  • Wodey E, Senhadji L, Pladys P, Carre F, Ecoffey C (2003) The relationship between expired concentration of sevoflurane and sympathovagal tone in children. Anesth Analg 97: 377–82

    Article  PubMed  CAS  Google Scholar 

  • Woolf RL, Crawford MW, Choo SM (1997) Dose-response of rocuronium bromide in children anesthetized with propofol: a comparison with succinylcholine. Anesthesiology 87: 1368–1372

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Universitäts-Kinderspital beider Basel (UKBB), Römergasse 8, 4005, Basel, Schweiz

    Prof. Dr. med. Franz J. Frei & PD Dr. med. Thomas Erb

  2. Children’s Hospital, 4800 Sand Point Way NE, 98105-0371, Seattle, WA, USA

    Dr. med. Christer Jonmarker

  3. Pediatric Anesthesia and Intensive Care, University Hospital, 22185, Lund, Sweden

    Dr. med. Olof Werner

  4. Zentrum Anästhesiologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland

    PD Dr. med. Robert Sümpelmann

Authors
  1. Prof. Dr. med. Franz J. Frei
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  2. PD Dr. med. Thomas Erb
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  3. Dr. med. Christer Jonmarker
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  4. Dr. med. Olof Werner
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  5. PD Dr. med. Robert Sümpelmann
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© 2004 Springer-Verlag Berlin Heidelberg

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Frei, F.J., Erb, T., Jonmarker, C., Werner, O., Sümpelmann, R. (2004). Anästhetika. In: Kinderanästhesie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-08072-6_4

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  • DOI: https://doi.org/10.1007/978-3-662-08072-6_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-08073-3

  • Online ISBN: 978-3-662-08072-6

  • eBook Packages: Springer Book Archive

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