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Endotoxinbindende Proteine, Antiendotoxinantikörper

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Intensivtherapie bei Sepsis und Multiorganversagen

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Zusammenfassung

Endotoxine sind integrale Bestandteile der äußeren Membran gramnegativer Bakterien, wie Enterobacteriaceae, Neisserien und Chlamydien. Sie sind bei zahlreichen physiologischen Membranfunktionen beteiligt und sind essentiell für das Wachstum von Bakterien und deren Überleben. Endotoxine repräsentieren die hitzestabilen 0-Antigene von Bakterien und definieren somit die Vielfalt der unterschiedlichen Serotypen. Schließlich zeigen Endotoxine eingroßes Spektrum biologischer Aktivitäten nach der Injektion in Tieren und in In-vitrö-Modellen [32].

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Authors
  1. P. Zabel
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Editors and Affiliations

  1. Städt. Krankenhaus Hildesheim Lehrkrankenhaus, Medizinischen Hochschule Hannover, Weinberg 1, 31134, Hildesheim, Deutschland

    Hans-Peter Schuster

  2. Klinikum Kröllwitz/Innere Medizin II, Martin-Luther-Universität, Ernst-Grube-Str. 40, 06097, Halle /Saale, Deutschland

    Karl Werdan

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Zabel, P. (2000). Endotoxinbindende Proteine, Antiendotoxinantikörper. In: Schuster, HP., Werdan, K. (eds) Intensivtherapie bei Sepsis und Multiorganversagen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-07962-1_6

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  • DOI: https://doi.org/10.1007/978-3-662-07962-1_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-07963-8

  • Online ISBN: 978-3-662-07962-1

  • eBook Packages: Springer Book Archive

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