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Molekulare Mechanismen der Pathogenität von Bakterien

  • Chapter
Immunsystem und Infektiologie

Part of the book series: Handbuch der Molekularen Medizin ((HDBMOLEK,volume 4))

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Zusammenfassung

Infektionskrankheiten wie Diarrhö, Typhus, Keuchhusten, Tuberkulose, Lepra, Gastroenteritis, Meningitis, Lungenentzündung etc., die durch pathogene Bakterien verursacht werden, stellen weltweit eines der größten Gesundheitsprobleme für den Menschen dar. Trotz verfügbarer Therapeutika, insbesondere Antibiotika, sind diese Krankheiten nach wie vor die häufigste Ursache für Mortalität und Morbidität bei Menschen, v. a. in Ländern der III. Welt. Wie die jährlichen WHO-Berichte belegen, gehören in diesen Ländern bakterielle Darminfektionen bei Kleinkindern nach wie vor zu den wichtigsten Gründen für die hohe Kindersterblichkeit. Das Problem wird wesentlich verschärft durch die erschreckend hohe Zunahme an Resistenzen gegenüber den wichtigsten Antibiotika in vielen pathogenen Bakterien [Jacoby 1996].

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Gross, R., Goebel, W. (1999). Molekulare Mechanismen der Pathogenität von Bakterien. In: Ganten, D., Ruckpaul, K. (eds) Immunsystem und Infektiologie. Handbuch der Molekularen Medizin, vol 4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-07865-5_8

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