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Molekulargenetische Grundlagen der Allergie: Ansätze für eine molekulare Therapie

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Immunsystem und Infektiologie

Part of the book series: Handbuch der Molekularen Medizin ((HDBMOLEK,volume 4))

Zusammenfassung

Prausnitz u. Küstner demonstrierten als Erste, daß es im Blut sensibilisierter Individuen einen Faktor gibt, der nach Übertragung auf nicht-allergische Spender zu einer Sensibilisierung führt [Prausnitz u. Küstner 1921]. Küstner war allergisch gegen Fisch, und eine Injektion seines Serums in die Haut von Prausnitz, der Pollenallergiker war, führte zu einer sofortigen Rötung und Schwellung der Haut, als anschließend Fischantigen in die sensibilisierte Stelle gespritzt wurde. Den möglicherweise verantwortlichen Faktor nannten die beiden Forscher Reagin.

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Authors
  1. Margitta Worm
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  2. Beate M. Henz
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Editors and Affiliations

  1. Max-Delbrück-Centrum für Molekulare Medizin (MDC), Robert-Rössle-Str. 10, D-13122, Berlin-Buch, Deutschland

    Detlev Ganten  & Klaus Ruckpaul  & 

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Worm, M., Henz, B.M. (1999). Molekulargenetische Grundlagen der Allergie: Ansätze für eine molekulare Therapie. In: Ganten, D., Ruckpaul, K. (eds) Immunsystem und Infektiologie. Handbuch der Molekularen Medizin, vol 4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-07865-5_5

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  • DOI: https://doi.org/10.1007/978-3-662-07865-5_5

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  • Print ISBN: 978-3-662-07866-2

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