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Tumors of Fibrous Tissue

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Imaging of Soft Tissue Tumors

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Abstract

Fibrous tissue consists of fibroblasts and an extracellular matrix containing both fibrillary structures (collagen, elastin) and nonfibrillary, gel-like ground substance. Both fibroblasts (spindle-shaped cells) and myofibroblasts, which are modified fibroblasts showing features common to fibroblasts and smooth muscle cells, produce procollagen and collagen Collagen is the main component of the extracellular matrix, forming a heterogeneous group of closely related, noncontractile structures varying in function and distribution. Elastin is the main component of elastic fibers that are closely associated with collagen fibers. The ground substance of connective tissue is glycosaminoglycans (mucopolysaccharides), the most common types being hyaluronic acid and chondroitin 4- and 6-sulfates. Both elastin and glycosaminoglycans are also synthesized by fibroblasts [17, 48].

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  1. A. M. De Schepper
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  2. J. E. Vandevenne
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Editors and Affiliations

  1. Department of Radiology, University Hospital of Antwerp, Wilrijkstraat 10, 2650, Edegem, Belgium

    Arthur M. De Schepper MD, PhD (Professor and Chairman), Paul M. Parizel MD, PhD (Staff Radiologist), Luc De Beuckeleer MD (Radiologist) & Filip Vanhoenacker MD (Staff Radiologist) (Professor and Chairman),  (Staff Radiologist),  (Radiologist) &  (Staff Radiologist)

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De Schepper, A.M., Vandevenne, J.E. (2001). Tumors of Fibrous Tissue. In: De Schepper, A.M., Parizel, P.M., De Beuckeleer, L., Vanhoenacker, F. (eds) Imaging of Soft Tissue Tumors. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-07856-3_10

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  • DOI: https://doi.org/10.1007/978-3-662-07856-3_10

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