Advertisement

Kutane B-Zell-Lymphome

  • L. Cerroni
  • H. Kerl

Zusammenfassung

Kutane B-Zell-Lymphome (KBZL) sind Neoplasien des Immunsystems, charakterisiert durch eine Proliferation von B-Lymphozyten, die ein gewebespezifisches „homing pattern“ mit Infiltration der Haut aufweisen. Diese Lymphome stellen eine sehr wichtige Gruppe der primären kutanen Lymphome dar. Wir wissen heute, dass die Häufigkeit der KBZL viel größer ist als allgemein angenommen wurde. Die Anwendung immunhistochemischer und molekularbiologischer Methoden hat gezeigt, dass viele der in der Vergangenheit als Pseudolymphome klassifizierten Tumoren Beispiele von KBZL repräsentieren.

Synonym

zentroblastisch-zentrozytisches Lymphom follikuläres Lymphom monozytoides B-Zell-Lymphom extra-nodales niedrig-malignes B-Zell-Lymphom vom MALT-Typ lymphoplasmozytoides Lymphom 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Bailey EM, Ferry JA, Harris NL, Mihm MC Jr, Jacobson JO, Duncan LM (1996) Marginal zone lymphoma (low-grade B-cell lymphoma of mucosa-associated lymphoid tissue type) of skin and subcutaneous tissue. A study of 15 patients. Am J Surg Pathol 20: 1011–1023PubMedCrossRefGoogle Scholar
  2. Burg G, Braun-Falco O (1983) Cutaneous lymphomas, pseudolymphomas and related disorders., Springer, Berlin, Heidelberg New YorkGoogle Scholar
  3. Cerroni L, Kerl H (1999) Diagnostic immunohistology: Cutaneous lymphomas and pseudolymphomas. Semin Cutan Med Surg 18: 64–70Google Scholar
  4. Cerroni L, Volkenandt M, Rieger E, Soyer HP, Kerl H (1994) bc1–2 protein expression and correlation with the inter-chromosomal 14;18 translocation in cutaneous lymphomas and pseudolymphomas. J Invest Dermatol 102: 231–235Google Scholar
  5. Cerroni L, Signoretti S, Höfler G. et al. ( 1997 a) Primary cutaneous marginal zone B-cell lymphoma. A recently described entity of low-grade malignant cutaneous B-cell lymphoma. Am J Surg Pathol 21: 1307–1315Google Scholar
  6. Cerroni L, Zöchling N, Pütz B, Kerl H (1997b) Detection of Borrelia burgdorferi in routinely-processed biopsy specimens of primary cutaneous B-cell lymphomas by PCR technique. J Cutan Pathol 24: 457–461PubMedCrossRefGoogle Scholar
  7. Cerroni L, Gatter K, Kerl H (1998) An illustrated guide to skin lymphoma. Blackwell, OxfordGoogle Scholar
  8. Cerroni L, Arzberger E, Pütz B et al. (2000) Primary cutaneous follicle center cell lymphoma with follicular growth pattern. Blood 95: 3922–3928PubMedGoogle Scholar
  9. Chang YT, Wong CK (1994) Primary cutaneous plasmacytomas. Clin Exp Dermatol 19: 177–180PubMedCrossRefGoogle Scholar
  10. Harris NL, Jaffe ES, Stein H et al. (1994) A revised European-American classification of lymphoid neoplasms: A proposal from the International Lymphoma Study Group. Blood 84: 1361–1392Google Scholar
  11. Hurt MA, Santa Cruz DJ (1990) Cutaneous inflammatory pseudotumor. Am J Surg Pathol 14: 764–773PubMedCrossRefGoogle Scholar
  12. Isaacson PG, Norton AJ (1994) Cutaneous lymphoma. In: Isaacson PG, Norton AJ (eds) Extranodal lymphomas. Churchill Livingstone, Edinburgh London Madrid Melbourne New York Tokyo, pp 172–176Google Scholar
  13. Jaffe ES, Harris NL, Stein H, Vardiman JW (eds) (2001) World health organization classification of tumours of haematopoietic and lymphoid tissues. IARC Press, LyonGoogle Scholar
  14. Kerl H, Cerroni L (1996) The morphologic spectrum of cutaneous B-cell lymphomas. Arch Dermatol 132: 1376–1377PubMedCrossRefGoogle Scholar
  15. Kerl H, Kresbach H (1979) Lymphoretikuläre Hyperplasien and Neoplasien der Haut. In: Schnyder UW (Hrsg) Spezielle pathologische Anatomie. Springer, Berlin Heidelberg New York, S 396–399Google Scholar
  16. LeBoit PE, McNutt NS, Reed JA, Jacobson M, Weiss LM (1994) Primary cutaneous immunocytoma. A B-cell lymphoma that can easily be mistaken for cutaneous lymphoid hyperplasia. Am J Surg Pathol 18: 969–978Google Scholar
  17. Muscardin LM, Pulsoni A, Cerroni L (2000) Primary cutaneous plasmacytoma. Report of a case with review of the literature. J Am Acad Dermatol 43: 962–965Google Scholar
  18. Pimpinelli N, Santucci M, Bosi A et al. (1989) Primary cutaneous follicular centre-cell lymphoma: A lymphoproliferative disease with favourable prognosis. Clin Exp Dermatol 14: 12–19Google Scholar
  19. Rijlaarsdam JU, van der Putte SCJ, Berti E et al. (1993) Cutaneous immunocytomas: A clinicopathologic study of 26 cases. Histopathology 23: 117–125PubMedCrossRefGoogle Scholar
  20. Santucci M, Pimpinelli N, Arganini L (1991) Primary cutaneous B-cell lymphoma: A unique type of low-grade lymphoma–Clinicopathologic and immunologic study of 83 cases. Cancer 67: 2311–2326PubMedCrossRefGoogle Scholar
  21. Tome R, Su WPD, Winkelmann RK, Smolle J, Kerl H (1990) Clinicopathologic study of cutaneous plasmacytoma. Int J Dermatol 29: 562–566CrossRefGoogle Scholar
  22. Vermeer MH, Geelen FAMJ, van Haselen CW et al. (1996) Primary cutaneous large B-cell lymphomas of the legs. A distinct type of cutaneous B-cell lymphoma with an intermediate prognosis. Arch Dermatol 132: 1304–1308Google Scholar
  23. Willemze R, Kerl H, Sterry W et al. (1997) EORTC classification for primary cutaneous lymphomas: A proposal from the Cutaneous Lymphoma Study Group of the European Organization for Research and Treatment of Cancer. Blood 90: 354–371Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • L. Cerroni
  • H. Kerl

There are no affiliations available

Personalised recommendations