Adnextumoren mit ekkriner Differenzierung

  • S. Kaddu
  • H.-P. Soyer
  • H. Kerl

Zusammenfassung

Die Klassifikation (Tabelle 32.1) ekkriner Tumoren ist immer noch nicht einheitlich und manchmal auch verwirrend. Einerseits wurden verschiedene Namen für Tumoren mit identischen histologischen Merkmalen in der Literatur verwendet, andererseits zeigen Adnextumoren mit ekkriner Differenzierung innerhalb einer Gruppe vielfältige histologische Merkmale. Außerdem ermöglichen sowohl immunohistochemische als auch ultrastrukturelle Untersuchungen bei einigen Entitäten keine exakte Zuordnung bezüglich ekkriner oder apokriner Differenzierung. So zeigen der „benigne“ Mischtumor der Haut und seine maligne Variante nur relativ selten eine ekkrine Differenzierung (ekkriner Typ), häufiger jedoch eine apokrine Differenzierung (apokriner Typ), weshalb die Mischtumoren im Kap. 31, „Adnextumoren mit apokriner Differenzierung“, abgehandelt werden (S. 689 u. 694).

Synonym

akrosyringeale Adenomatose ekkrine Syringofibroadenomatose (Mascaro) akrosyringealer Nävus (Weedon und Lewis) Akrospirom solid-zystisches Hidradenom klarzelliges Hidradenom noduläres ekkrines Hidradenom poroide Tumoren 

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Literatur

  1. Abenoza P, Ackerman AB (1990) Neoplasms with eccrine differentiation. Lea and Febiger, PhiladelphiaGoogle Scholar
  2. Santa Cruz DJ (1987) Sweat gland carcinomas: A comprehensive review. Semin Diagn Pathol 4: 38–74Google Scholar
  3. Watanabe S, Ichikawa E, Takanashi S, Takahashi H (1993) Immunohistochemical localization of cytokeratins in normal eccrine glands, with monoclonal antibodies in routinely processed, formalin-fixed, paraffin-embedded sections. J Am Acad Dermatol 28: 203–212PubMedCrossRefGoogle Scholar
  4. Cebreiro C, Sanchez-Aguilar D, Gomez-Centeno P, Fernandez-Redondo V, Toribio J (1998) Eccrine angiomatous hamartoma: Report of seven cases. Clin Exp Dermatol 23: 267–270Google Scholar
  5. Kopera D, Soyer HP (1992) Ekkrines Hamartom der Schweißdrüsen unter dem Bild einer lokalisierten unilateralen Hyperhidrose. Hautarzt 43: 587–589PubMedGoogle Scholar
  6. Smith C, Montesinos E, Revert A, Ramon D, Molina I, Jorda E (1996) Eccrine angiomatous hamartoma: Report of three patients. Pediatr Dermatol 13: 139–142Google Scholar
  7. Sulica RL, Kao GF, Sulica VI, Penneys NS (1994) Ekkrine angiomatous hamartoma (nevus): Immunohistochemical findings and review of the literature. J Cutan Pathol 21: 71–75Google Scholar
  8. Kanitakis J, Zambruno G, Euvrard S, Hermier C, Thivolet J (1987) Eccrine syringofibroadenoma. Immunohistologi-cal study of a new case. Am J Dermatopathol 9: 37–40Google Scholar
  9. Komine M, Hattori N, Tamaki K (woo) Eccrine syringo-fibroadenoma (Mascaro): An immunohistochemical study. Am J Dermatopathol 22: 171–175Google Scholar
  10. Mascaro JM (1963) Considerations sur les tumeurs fibro-epithéliales: le syringofibroadénome eccrine. Ann Der-matol Syphil 90: 146–153Google Scholar
  11. Mehregan AH, Marufi M, Medenica M (1985) Eccrine syringofibroadenoma (Mascaro). Report of two cases. J Am Acad Dermatol 13: 433–436Google Scholar
  12. Weedon D, Lewis J (1977) Acrosyringeal naevus. J Cutan Pathol 4: 166–168PubMedCrossRefGoogle Scholar
  13. Gartmann H, Tritsch H (1971) Noduläres Hidradenom mit krebsiger Umwandlung. Z Haut Geschl Kr 46: 163–168Google Scholar
  14. Hernandez-Perez E, Cestoni-Parducci R (1985) Nodular hidradenoma and hidradenocarcinoma. A 10-year review. J Am Acad Dermato112: 15–20Google Scholar
  15. Hunt SJ, Santa Cruz DJ, Kerl H (1990) Giant eccrine acrospiroma. J Am Acad Dermatol 23: 663–668PubMedCrossRefGoogle Scholar
  16. Wilson-Jones E (1971) Pigmented nodular hidradenoma. Arch Dermatol 104: 117–123PubMedCrossRefGoogle Scholar
  17. Abenoza P, Ackerman AB (1990) Neoplasms with eccrine differentiation. Lea and Febiger, PhiladelphiaGoogle Scholar
  18. Harvell JD, Kerschmann RL, LeBoit PE (1996) Eccrine or apocrine poroma? Six poromas with divergent adnexal differentiation. Am J Dermatopathol 18: 1–9PubMedCrossRefGoogle Scholar
  19. Hu CH, Marques AS, Winkelmann RK (1978) Dermal duct tumor: A histochemical and electron microscopic study. Arch Dermatol 114: 1659–1664Google Scholar
  20. Penneys NS, Ackerman AB, Indgin SN, Mandy SH (1970) Eccrine poroma: Two unusual variants. Br J Dermatol 82: 613–615Google Scholar
  21. Rahbari H (1983) Hidroacanthoma simplex–a review of 15 cases. Br J Dermatol 109: 219–225PubMedCrossRefGoogle Scholar
  22. Castro C, Winkelmann RK (1974) Spiradenoma. Histochemical and electron microscopic study. Arch Dermatol 109: 40–48Google Scholar
  23. Eich N, Lechner W (1985) Ekkrines Spiradenom. Hautarzt 36: 240–241PubMedGoogle Scholar
  24. Mambo NC (1983) Eccrine spiradenoma: Clinical and pathologic study of 49 tumors. J Cutan Pathol 10: 312–320PubMedCrossRefGoogle Scholar
  25. Soyer HP, Kerl H, Ott A (1998) Spiradenocylindroma–morethan a coincidence? Am J Dermatopathol 20: 315–317PubMedCrossRefGoogle Scholar
  26. Wright S, Ryan J (1990) Multiple familial eccrine spiradenoma with cylindroma. Acta Derm Venereol 70: 79–82PubMedGoogle Scholar
  27. Ambrojo P, Requena Caballero L, Aguilar Martinez A, Sanchez Yus E, Furio V (1989) Clear-cell syringoma. Immunohistochemistry and electron microscopy study. Dermatologica 178: 164–166Google Scholar
  28. Feibelman CE, Maize JC (1984) Clear-cell syringoma. A study by conventional and electron microscopy. Am J Dermatopathol 6: 139–150Google Scholar
  29. Henner MS, Shapiro PE, Ritter JH, Leffell DJ, Wick MR (1995) Solitary syringoma. Report of five cases and clinico-pathologic comparison with microcystic adnexal carcinoma of the skin. Am J Dermatopathol 17: 465–470Google Scholar
  30. Patrizi A, Neri I, Marzaduri S, Varotti E, Passarini B (1998) Syringoma: A review of twenty-nine cases. Acta Derm Venereol 78: 460–462Google Scholar
  31. Sala GP, Marinaro P, Rossi E, Nicoletti A, Bramati SP, Galbiati G (1990) Einseitige nävoide Syringome. Hautarzt 41: 272–273PubMedGoogle Scholar
  32. Crain RC, Helwig EB (1961) Dermal cylindroma (dermal eccrine cylindroma). Am J Clin Pathol 35: 504–515PubMedGoogle Scholar
  33. Goette DK, McConnell MA, Fowler VR (1982) Cylindroma and eccrine spiradenoma coexistent in the same lesion. Arch Dermatol 118: 274–274PubMedCrossRefGoogle Scholar
  34. Korting HC, Konz B (1982) Koinzidenz multipler Zylindrome mit Trichoepitheliomen ( Brooke-Spiegler-Syndrome ). Hautarzt 33: 34–46Google Scholar
  35. Martinez W, Yebra MT, Arnal F, Casado M, Borbujo J (1992) Multiple linear cylindromas. J Am Acad Dermatol 26: 821–824PubMedCrossRefGoogle Scholar
  36. Urbach F, Graham JH, Goldstein J. Munger BL (1963) Dermal eccrine cylindroma. Arch Dermatol 88: 880–894CrossRefGoogle Scholar
  37. Gartmann H (1984) Ekkrines Porokarzinom. Z Hautkr 60: 555–562Google Scholar
  38. Mehregan AH, Hashimoto K, Rahbari H (1983) Eccrine adenocarcinoma. A clinicopathologic study of 35 cases. Arch Dermatol 119: 104–114PubMedCrossRefGoogle Scholar
  39. Robson A, Greene J, Ansari N, Kim B, Seed PT, McKee PH, Calonje E (2001) Eccrine porocarcinoma (malignant eccrine poroma): A clinicopathologic study of 69 cases. Am J Surg Pathol 25: 710–720PubMedCrossRefGoogle Scholar
  40. Will R, Coldiron B (2000) Recurrent clear cell hidradenoma of the foot. Dermatol Surg 26: 685–686PubMedCrossRefGoogle Scholar
  41. Yildirim S, Akoz T, Apaydin I, Ege GA, Gideroglu K (2000) Malignant clear cell hidradenoma with giant metastasis to the axilla. Ann Plast Surg 45: 102PubMedCrossRefGoogle Scholar
  42. Argenyi ZB, Nguyen AV, Balogh K, Sears JK, Whitaker DC (1992) Malignant eccrine spiradenoma. A clinicopathologic study. Am J Dermatopathol 14: 381–390Google Scholar
  43. Lin PY, Fatteh SM, Lloyd KM (1987) Malignant transformation in a solitary dermal cylindroma. Arch Pathol Lab Med n1: 765–767Google Scholar
  44. Lo JS, Peschen M, Snow SN, Oriba HA, Mohs FE (1991) Malignant cylindroma of the scalp. J Dermatol Surg Oncol 17: 897–901PubMedCrossRefGoogle Scholar
  45. Rütten A, Kutzner H, Sahre EM (1993) Spiradenokarzinom. Aktuelle Dermatol 19: 157–159Google Scholar
  46. Urbanski SJ, From L, Abramowicz A, Joaquin A, Luk SC (1985) Metamorphosis of dermal cylindroma: Possible relation to malignant transformation. Case report of cutaneous cylindroma with direct intracranial invasion. J Am Acad Dermato1. 12: 188–195CrossRefGoogle Scholar
  47. Chung CK, Heffernan AH (1971) Clear cell hidradenoma with metastasis. Case report with a review of the literature. Plast Reconstr Surg 48: 177–180Google Scholar
  48. Dissanayake RV, Salm R (1980) Sweat-gland carcinomas: Prognosis related to histological type. Histopathology 4: 445–466Google Scholar
  49. Santa Cruz DJ (1987) Sweat gland carcinomas: A comprehensive review. Semin Diagn Pathol 4: 38–74Google Scholar
  50. Suster S, Wong TY (1994) Polymorphous sweat gland carcinoma. Histopathology 25: 31–39PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • S. Kaddu
  • H.-P. Soyer
  • H. Kerl

There are no affiliations available

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