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Adnextumoren mit apokriner Differenzierung

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Histopathologie der Haut

Zusammenfassung

Kutane Adnextumoren mit duktaler Differenzierung unterteilt man üblicherweise in Tumoren mit apokriner und ekkriner Differenzierung. Die morphologische Unterscheidung ist nicht immer eindeutig, weil die Drüsenausführungsgänge apokriner und ekkriner Adnextumoren morphologisch häufig nicht unterscheibar sind. Das klassische morphologische Merkmal für Adnextumoren mit apokriner Differenzierung, die so genannte „Dekapitationsekretion“, kann man gelegentlich auch bei Adnextumoren mit ekkriner Differenzierung beobachten. Deshalb gibt es noch immer Debatten über die Histogenese einiger dieser kutanen Adnextumoren mit duktaler Differenzierung. Der Großteil der apokrinen Adnextumoren ist gutartig, und nur selten wurden bösartige Varianten beschrieben. Maligne apokrine Adnextumoren weisen ein breites morphologisches Spektrum auf, wodurch manchmal eine eindeutige histologische Klassifikation erschwert wird (Tabelle 31.1).

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Kaddu, S., Soyer, HP., Kerl, H. (2003). Adnextumoren mit apokriner Differenzierung. In: Kerl, H., Garbe, C., Cerroni, L., Wolff, H.H. (eds) Histopathologie der Haut. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-07784-9_31

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  • DOI: https://doi.org/10.1007/978-3-662-07784-9_31

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