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Adnextumoren mit Talgdrüsendifferenzierung

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Histopathologie der Haut

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Zusammenfassung

Alle Talgdrüsenläppchen, die einen Haarfollikel im oberen Anteil umgeben, bilden zusammen eine Talgdrüse. Die Talgdrüsenläppchen sind über einen oder mehrere Talgdrüsenausführungsgänge mit dem Infundibulum des Haarfollikels verbunden. Morphologisch bestehen Talgdrüsenläppchen aus einer peripheren undifferenzierten germinativen Zellschicht und den zentral gelegenen ausdifferenzierten vakuolisierten Sebozyten. Das Zytoplasma der ausdifferenzierten Talgdrüsenzellen ist vollständig mit kleinen Lipidvakuolen ausgefüllt, die den zentral gelegenen Zellkern mehrfach eindellen. In Richtung des Talgdrüsenausführungsganges ist eine zunehmende Pyknose der Zellkerne und Desintegration der äußeren Zellmembran zu beobachten. Die gesamte kernlose Talgdrüsenzelle wird als Talg in den Haarfollikel abgegeben. Dieser Vorgang stellt eine holokrine Sekretion dar.

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Authors
  1. A. Rütten
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Editors and Affiliations

  1. Universitätsklinik für Dermatologie und Venerologie, Karl-Franzens-Universität Graz, Auenbruggerplatz 8, A-8036, Graz, Österreich

    Helmut Kerl  & Lorenzo Cerroni  & 

  2. Universitäts-Hautklinik, Eberhard-Karls-Universität Tübingen, Liebermeisterstraße 25, D-72076, Tübingen, Deutschland

    Claus Garbe

  3. Klinik für Dermatologie und Venerologie, Universität zu Lübeck, Ratzeburger Allee 160, D-23562, Lübeck, Deutschland

    Helmut H. Wolff

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Rütten, A. (2003). Adnextumoren mit Talgdrüsendifferenzierung. In: Kerl, H., Garbe, C., Cerroni, L., Wolff, H.H. (eds) Histopathologie der Haut. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-07784-9_30

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  • DOI: https://doi.org/10.1007/978-3-662-07784-9_30

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-07785-6

  • Online ISBN: 978-3-662-07784-9

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