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Bindegewebekrankheiten

  • U.-F. Haustein
  • M. Mittag

Zusammenfassung

Die systemsiche Sklerodermie stellt eine chronische Bindegewebeerkrankung mit Verdickung und Fibrose der Haut und inneren Organe unter Beteiligung des Gefäßsystems (Raynaud-Phänomen) und Dysregulation des Immunsystems bei unbekannter Ätiologie dar. Neben der systemischen existiert noch die umschriebene Sklerodermie (Morphea), die beide die gleichen histologischen Veränderungen aufweisen und sehr selten gemeinsam vorkommen oder ineinander übergehen können. Führende Phänomene der systemischen Form sind proximale Sklerodermie (Stammbetonung), Sklerodaktylie, grübchenförmige Fingernarben und bibasiläre interstitielle Lungenfibrose (Kriterien des amerikanischen College für Rheumatology).

Synonym

zirkumskripte Sklerodermie Shulman-Syndrom „white spot disease“ Balanitis xerotica obliterans Kraurosis vulvae Scleroedema adultorum Buschke Grönblad-Strandberg-Syndrom Elastolysis Dermatochalasis makulöse Atrophie 

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Copyright information

© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • U.-F. Haustein
  • M. Mittag

There are no affiliations available

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