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Sources of Information on the Occurrence of Chemical Contact Allergens

  • M.-A. Flyvholm

Abstract

Information on the occurrence of chemical contact allergens is necessary for the prevention and treatment of allergic contact dermatitis. The ideal situation is access to a reliable, easy and quick detection and identification of contact allergens in the environment. Each different method used to obtain this information has its own advantages and drawbacks depending on the nature or the origin of the allergen(s) and product(s) in question and the context in which the information will be used. For example, in the clinical elucidation of the cause of allergic contact dermatitis, a throughout chemical separation and identification of constituents in a complex product is the ideal for revealing the offending allergen. For governmental agencies planning regulation of population exposure to allergens, overviews on exposure, based on national databases of chemical products and including information on product composition for the relevant product categories, will be much more useful. Ideally, all products should be labelled with ingredient listings including all contact allergens. For cosmetics, this situation is partly realised through the 6th Amendment of the European Union (EU) Cosmetics Directives, although fragrances are not included in the declaration. For chemical products, the value of the labelling is reduced by the threshold of 1% given in the Dangerous Preparations Directive for labelling of products containing skin sensitisers (R43 “may cause contact sensitisation by skin contact”).

Keywords

European Union Contact Dermatitis Product Category Chemical Product Allergic Contact Dermatitis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Cronin E (1991) Formaldehyde is a significant allergen in women with hand eczema. Contact Dermatitis 25:276–282PubMedCrossRefGoogle Scholar
  2. De Groot AC, Weijland JW (1997) Conversion of common names of cosmetic allergens to the INCI nomenclature. Contact Dermatitis 37:145–150PubMedCrossRefGoogle Scholar
  3. Dooms-Goossens A, Dooms M, Drieghe J (1995) Computers and patient information systems. In: Rycroft RJG, Menné T, Frosch PJ (eds) Textbook of contact dermatitis, 2nd edn. Springer, Berlin Heildelberg New York, pp 771–784Google Scholar
  4. Edman B (1988) The usefulness of detailed information to patients with contact allergy. Contact Dermatitis 19:43–47PubMedCrossRefGoogle Scholar
  5. Flyvholm M-A (1996) Prevention by exposure assessment. Curr Probl Dermatol 25:97–105PubMedGoogle Scholar
  6. Flyvholm M-A (1997) Formaldehyde exposure at the workplace and in the environment. Allergologie 5:225–231Google Scholar
  7. Flyvholm M-A, Andersen P (1993) Identification of formaldehyde releasers and occurrence of formaldehyde and formaldehyde releasers in registered chemical products. Am J Ind Med 24:533–552PubMedCrossRefGoogle Scholar
  8. Flyvholm M-A, Menné T (1992) Allergic contact dermatitis from formaldehyde. A case study focussing on sources of formaldehyde exposure. Contact Dermatitis 27:27–36PubMedCrossRefGoogle Scholar
  9. Flyvholm M-A, Andersen P, Beck ID, Brandorff NP (1992) PROBAS: The Danish Product Register Data Base — a national register of chemical substances and products. J Hazardous Materials 30:59–69CrossRefGoogle Scholar
  10. Flyvholm M-A, Menné T, Maibach HI (1995) Skin allergy: exposures and dose-response relationships. In: Vos JG, Younes M, Smith E (eds) Allergic hypersensitivities induced by chemicals. Recommendations for prevention. CRC Press, Boca Raton, pp 261–285Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2000

Authors and Affiliations

  • M.-A. Flyvholm

There are no affiliations available

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