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Zellkulturtechniken, Zellmodelle und Tissue Engineering

  • Chapter
Grundlagen der Molekularen Medizin

Zusammenfassung

Die moderne Zell- und Molekularbiologie ist ohne den Einsatz von Zell- und Gewebekulturen nicht denkbar. Die „In-vitro-Zellbiologie“ bildet heute die Grundlage für die Aufklärung grundlegender Wachstums- und Differenzierungsprozesse tierischer und pflanzlicher Systeme. Säugerzellkulturen finden Einsatz in der biomedizinischen Grundlagenforschung, der Virologie, Immunologie, Strahlenbiologie und Krebsforschung. Darüber hinaus spielen Zellkulturen in der medizinischen Diagnostik (u. a. pränatale Diagnose, Tumordiagnostik), zur Herstellung von biologischen Wirkstoffen für Diagnostik, Prophylaxe und Therapie, zur Produktion von Impfstoffen und Arzneimitteln und für toxikologische Untersuchungen eine große Rolle. Durch neueste Entwicklungen auf den Gebieten der Stammzellbiologie und des Tissue engineering werden Zellkulturen mehr und mehr Eingang in die regenerative Medizin finden.

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Authors
  1. Anna M. Wobus
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  1. Max-Delbrück-Centrum für Molekulare Medizin, Robert-Rössle-Str. 10, 13122, Berlin-Buch, Deutschland

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Wobus, A.M. (2003). Zellkulturtechniken, Zellmodelle und Tissue Engineering. In: Ganten, D., Ruckpaul, K. (eds) Grundlagen der Molekularen Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-07588-3_9

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  • DOI: https://doi.org/10.1007/978-3-662-07588-3_9

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