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Mitochondriale DNA des Menschen

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Grundlagen der Molekularen Medizin

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Zusammenfassung

Ein Hauptmerkmal eukaryontischer Organismen ist der Besitz von Mitochondrien, in sich abgeschlossenen Zellorganellen, als Bestandteile des Zytoplasma. Mitochondrien sind zumeist stäbchenförmig und messen zwischen 0,2 und 1 tm im Durchmesser und 2–8 μm in Längsrichtung. Ihre Zahl schwankt je nach Zelltyp zwischen wenigen Dutzenden in den Spermien und primordialen Keimzellen bis zu Zehntausenden in Leberzellen oder reifen Oozyten. Einige Protisten besitzen sogar lediglich ein singuläres Mitochondrium (Trypanosomen, Physarum).

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Authors
  1. Bernd Wissinger
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  1. Max-Delbrück-Centrum für Molekulare Medizin, Robert-Rössle-Str. 10, 13122, Berlin-Buch, Deutschland

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Wissinger, B. (2003). Mitochondriale DNA des Menschen. In: Ganten, D., Ruckpaul, K. (eds) Grundlagen der Molekularen Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-07588-3_4

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  • DOI: https://doi.org/10.1007/978-3-662-07588-3_4

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