Studies on the Cardiovascular Effects of Gallopamil
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The effects of gallopamil (Research code no. D 600, Procorum) have been exhaustively studied on isolated heart preparations and the arterial musculature, whereas there is relatively little information on the cardiovascular effects of gallopamil in intact animals (for review of literature see Flaim and Zelis 1982; Weiss 1981). This is a report on some aspects of the effect of gallopamil on the ischaemic and hypoxic heart and on genetically induced hypertension. In view of the importance of the capacitance vessels in respect of cardiac function, gallopamil was also tested for its relaxant effects on veins.
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