Abstract
Sjögren’s syndrome (SS) is a chronic autoimmune disease of unknown aetiology, characterized by lymphocyte infiltration of exocrine glands resulting in xerostomia and keratoconjunctivitis sicca. In more than one-third of patients, extraglandular manifestations, such as skin, lung, kidney, liver, muscle and blood vessel involvement, can occur. SS can be found alone (primary SS) or in association with other autoimmune diseases, such as rheumatoid arthritis, systemic lupus erythematosus and scleroderma (secondary SS). Five per cent of patients may develop B-cell lymphoma.
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Further reading
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Tzioufas, A.G., Moutsopoulos, H.M. (2003). Sjögren’s syndrome. In: Katsambas, A.D., Lotti, T.M. (eds) European Handbook of Dermatological Treatments. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-07131-1_87
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DOI: https://doi.org/10.1007/978-3-662-07131-1_87
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