Abstract
Drug-induced pemphigus (DIP) is a rare but well-established variety of pemphigus. Several cases have been described worldwide since it was first reported in 1951 in Italy. Two patterns of association have been observed in DIP. In the first group the drug acts as the major aetiological factor, resulting in pemphigus which is usually mild and responds favourably on stopping the drug. In the other group, the drug only acts as a triggering factor in an immunologically and genetically predisposed individual, leading to the development of idiopathic pemphigus, the course of the disease not being influenced thereafter by the removal of the drug.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Further reading
Brenner S, Bialy-Golan A, Anhalt GJ. Recognition of pemphigus antigens in drug-induced pemphigus vulgaris and pemphigus foliaceus. J Am Acad Dermatol 1997; 36: 919–23
Brenner S, Bialy-Golan A, Ruocco V. Drug-induced pemphigus. Clin Dermatol 1998; 16 (3): 393–7.
Landau M, Brenner S. Histopathologic findings in drug-induced pemphigus. Am J Dermatopathol 1997; 19 (4): 411–14.
Mutasim DF, Pelc NJ, Anhalt GJ. Drug-induced pemphigus. Dermatol Clin 1993; 11 (3): 463–71.
Ogata K, Nakajima H, Ikeda M et al Drug-induced pemphigus foliaceus with features of pemphigus vulgaris. Br J Dermatol 2001; 144 (2): 421–2.
Ruocco V, De Angelis E, Lombardi ML. Drug-induced pemphigus. II. Pathomechanisms and experimental investigations. Clin Dermatol 1993; 11 (4): 507–13.
Toth GG, Jonkman MF. Successful treatment of recalcitrant penicillamine-induced pemphigus foliaceus by low-dose intravenous immunoglobulins. Br J Dermatol 1999; 141 (3): 583–5.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2003 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Albert, S., Black, M.M. (2003). Drug-induced pemphigus. In: Katsambas, A.D., Lotti, T.M. (eds) European Handbook of Dermatological Treatments. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-07131-1_24
Download citation
DOI: https://doi.org/10.1007/978-3-662-07131-1_24
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-05657-4
Online ISBN: 978-3-662-07131-1
eBook Packages: Springer Book Archive