Die Onkologie pp 1815-1846 | Cite as

Myelodysplastische Syndrome

  • A. Ganser


Seit dem ersten publizierten Bericht über therapierefraktäre Anämien unklarer Ätiologie vor mehr als sechzig Jahren (Rhoads u. Barker 1938), waren bis Anfang der achtziger Jahre verschiedene Bezeichnungen für die heutzutage als myelodysplastische Syndrome (MDS) bezeichnete Krankheitsgruppe gebräuchlich: präleukämische Anämie, Präleukämie, hämatopoetische Dysplasie, dysmyelopoetisches Syndrom, refraktäre Anämie, erworbene sideroachrestische Anämie, chronische erythrämische Myelose, Oligoleukämie, oligoblastäre Leukämie, „smoldering“ Leukämie, subakute myeloische Leukämie u. a. Im Jahre 1982 wurde schließlich von der FranzösischAmerikanisch-Britischen (FAB) Arbeitsgruppe derTerminus „myelodysplastische Syndrome“ (MDS) geprägt, der sich seitdem durchgesetzt hat (Bennett et al.1982).


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