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Apudome: Neuroendokrine Tumoren des Gastrointestinaltrakts

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Zusammenfassung

Für die Nomenklatur der endokrinen Tumoren des Gastrointestinaltrakts werden die in der Übersicht zusammengefassten Begriffe synonym verwendet. Der Terminus „Karzinoid“ ist streng genommen den endokrinen Tumoren des Magen-Darm-Trakts (Vorder-, Mittel- und Hinterdarm) und den sich aus dem Vorderdarm abgeleiteten Organsystemen wie dem Bronchialsystem vorbehalten (⊡ Tabelle 67.1; Arnold 1997). Endokrine Pankreastumoren fallen danach nicht unter den Karzinoidbegriff, da diese sich aus den Langerhans-Inseln und nicht aus dem diffusen endokrinen Zellsystem des Gastrointestinaltrakts entwickeln. Zumindest bei Vertebraten entstehen die Langerhans-Inseln aus einem eigenständigen Inselorgan, das während der Ontogenese mit dem exokrinen Pankreasanteil verschmilzt.

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Arnold, R., Simon, B., Göke, R. (2004). Apudome: Neuroendokrine Tumoren des Gastrointestinaltrakts. In: Die Onkologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-06670-6_67

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