Die Onkologie pp 535-562 | Cite as

Hochdosistherapie und Stammzelltransplantation

  • C. Scheffold
  • W. E. Berdel
  • J. Kienast


In den 50 Jahern seit den ersten llinischen Transplantationseversuchen hat sich die hämatopoetische Stammzelltransplantation zu einem wichtigen Element der modernen Tumortherapie und der Behandlung nichtmaligner Stammzell- und Immundefekte sowie bestimmter hereditärer Stoffwechselerkrankungen entwickelt. Neue Indikationsgebiete werden erschlossen und Anwendungsgrenzen, bedingt durch Alter,Vorbehandlung und Komorbidität der Patienten, verschieben sich. Möglich wurde dieser Fortschritt durch eine Vielzahl paralleler Entwicklungen auf den Gebieten der Transplantationsimmunologie und Stammzellbiologie sowie der immunsuppressiven und supportiven Therapie.


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© Springer-Verlag Berlin Heidelberg 2004

Authors and Affiliations

  • C. Scheffold
  • W. E. Berdel
  • J. Kienast

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