Akutes Leberversagen

  • K. H. W. Böker
  • M. P. Manns


Als akutes Leberversagen bezeichnet man den Ausfall der Leberfunktion bei Patienten, die vorher keine chronische Leberkrankheit hatten.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Aggarwal S, Kramer D, Yonas H et al. (1994) Cerebral hemodynamic and metabolic changes in fulminant hepatic failure: a retrospective study. Hepatology 19: 80–87PubMedCrossRefGoogle Scholar
  2. 2.
    Berman DH, Leventhal RI, Gavaler JS et al. (1991) Clinical differentiation of fulminant Wilsonian hepatitis from other causes of hepatic failure. Gastroenterology 100: 1129–1134PubMedGoogle Scholar
  3. 3.
    Bismuth H, Samuel D, Castaing D et al. (1996) Liver transplantation in Europe for patients with acute liver failure. Semin Liver Dis 16: 415–425PubMedCrossRefGoogle Scholar
  4. 4.
    Blei AT, Olafsson S, Webster Set al. (1993) Complications of intracranial pressure monitoring in fulminant hepatic failure. Lancet 341: 157–158PubMedCrossRefGoogle Scholar
  5. 5.
    Devlin J, Ellis AE, McPeake J et al. (1997) N-acetylcysteine improves indocyanine green extraction and oxygen transport during hepatic dysfunction. Crit Care Med 25: 236–242PubMedCrossRefGoogle Scholar
  6. 6.
    Ellis A, Wendon J (1996) Circulatory, respiratory, cerebral, and renal derangements in acute liver failure: pathophysiology and management. Semin Liver Dis 16: 379–388PubMedCrossRefGoogle Scholar
  7. 7.
    Fiaccadori F, Pedretti G, Ferrari C et al. (1991) Insulin and glucagon levels in fulminant hepatic failure in man. Dig Dis Sci 36: 801808Google Scholar
  8. 8.
    Gimson A, Tedder R, White Y (1983) Serological markers in fulminant Hepatitis B. Gut 24: 615PubMedCrossRefGoogle Scholar
  9. 9.
    Gubernatis G, Pichlmayr R, Kemnitz J et al. (1991) Auxiliary partial orthotopic liver transplantation (APOLT) for fulminant hepatic failure: first successful case report. World J Surg 15: 660–605PubMedCrossRefGoogle Scholar
  10. 10.
    Gyr K, Meier R (1991) Flumazenil in the treatment of portal systemic encephalopathy–an overview. Intensive Care Med 17 (Suppl 1): 39–42CrossRefGoogle Scholar
  11. 11.
    Häussinger D, Laubenberger J, vom Dahl S et al. (1994) Proton magnetic resonance spectroscopy studies on human brain myoinositol in hyperosmolarity and hepatic encephalopathy. Gastroenterology 107: 1475–1480PubMedCrossRefGoogle Scholar
  12. 12.
    Krowka MJ (1993) Clinical management of hepatopulmonary syndrome. Sem Liver Dis 13: 414–422CrossRefGoogle Scholar
  13. 13.
    Lake JR, Sussman NL (1995) Determining prognosis in patients with fulminant hepatic failure: when you absolutely, positively have to know the answer [editorial]. Hepatology 21: 879–882PubMedCrossRefGoogle Scholar
  14. 14.
    Lee WM (1996) Management of acute liver failure. Semin Liver Dis 16: 369–378PubMedCrossRefGoogle Scholar
  15. 15.
    Liang TJ, Hasegawa K, Rimon N et al. (1991) A hepatitis B virus mutant associated with an epidemic of fulminant hepatitis. N Engl J Med 324: 1705–1709PubMedCrossRefGoogle Scholar
  16. 16.
    McConnel JR, Antonson DL, Ong CS et al. (1995) Proton spectroscopy of brain glutamine in acute liver failure. Hepatology 22: 69–74CrossRefGoogle Scholar
  17. 17.
    McGuire BM, Sielaff TD, Nyberg SL et al. (1995) Review of support systems used in the management of fulminant hepatic failure. Dig Dis 13: 379–388PubMedCrossRefGoogle Scholar
  18. 18.
    Munoz SJ (1993) Difficult management problems in fulminant hepatic failure. Semin Liver Dis 13: 395–413PubMedCrossRefGoogle Scholar
  19. 19.
    O’GradyJG (1997) Paracetamol hepatotoxicity: how to prevent.J R Soc Med 90: 368–370Google Scholar
  20. 20.
    Pereira LM, Langley PG, Hayllar KM et al. (1992) Coagulation factor V and VIIIN ratio as predictors of outcome in paracetamol induced fulminant hepatic failure: relation to other prognostic indicators. Gut 33: 98–102PubMedCrossRefGoogle Scholar
  21. 21.
    Pereira SP, Langley PG, Williams R (1996) The management of abnormalities of hemostasis in acute liver failure. Semin Liver Dis 16: 403–414PubMedCrossRefGoogle Scholar
  22. 22.
    Pohl L (1990) Drug induced allergic hepatitis. Semin Liver Dis 10: 305–315PubMedCrossRefGoogle Scholar
  23. 23.
    Riely CA (1994) Hepatic disease in pregnancy. Am J Med 96:18 S-22 SGoogle Scholar
  24. 24.
    Stremmel W, Meyerrose KW, Niederau C et al. (1991) Wilson disease: clinical presentation, treatment, and survival. Ann Intern Med 11: 720–726CrossRefGoogle Scholar
  25. 25.
    Theilmann L, Solbach C,Toex U et al. (1992) Role of hepatitis C virus infection in German patients with fulminant and subacute hepatic failure. Eur J Clin Invest 22: 569–571PubMedCrossRefGoogle Scholar
  26. 26.
    Van Pelt F, Straub P, Manns M (1995) Molecular basis of drug induced immunological liver injury. Semin Liver Dis 15: 283–300PubMedCrossRefGoogle Scholar
  27. 27.
    Williams R (1996) Classification, etiology, and considerations of outcome in acute liver failure. Semin Liver Dis 16: 343–348PubMedCrossRefGoogle Scholar
  28. 28.
    Williams R, Wendon J (1994) Indications for orthotopic liver transplantation in fulminant liver failure. Hepatology 20: 5–10CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2004

Authors and Affiliations

  • K. H. W. Böker
  • M. P. Manns

There are no affiliations available

Personalised recommendations