Abstract
Single Photon Emission Tomographic (SPET) imaging overcomes the loss of contrast suffered by planar images, which impairs the detectability of small lesions, particularly those which are deep lying and which exhibit reduced radionuclide accumulation. The reconstructed data can also be reoriented into, for example, coronal or sagittal sections, for better visualisation of the relative positions of activity distributions, which may help to localise the position of abnormalities more accurately. The technique also has the potential to quantify the regional distribution of activity, which allows representation of the activity distribution in units of MBq ml-1 rather than just counts per pixel, and thus better indicates organ function and radiation dosimetry (Rosenthal et al. 1995; Fleming and Alaamer 1996). A number of acquisition and processing factors are peculiar to SPET and, although software for single photon tomographic imaging was introduced in the mid 1980s, a range of imaging protocols are in use and are sometimes inappropriate, which demonstrates the on-going need to encourage the correct use of the instrumentation (Heikkinen et al. 1999). The image data is heavily and sophisticatedly processed. This includes attenuation correction and scatter compensation which can improve image resolution and contrast, significantly. It is possible to reconstruct images that are far from optimum. Artefacts, which would have been easily recognised in the raw images, can become camouflaged.
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Abbreviations
- 2D:
-
two dimension
- 3D:
-
three dimension
- CT:
-
computed tomography
- ERNA:
-
equilibrium radionuclide angiography
- FOV:
-
field of view
- FWHM:
-
full width at half maximum
- LEGP:
-
low energy general purpose
- LEHR:
-
low energy high resolution
- LVEF:
-
left ventricular ejection fraction
- MPI:
-
myocardial perfusion imaging
- PHA:
-
pulse height analyser
- ROI:
-
region of interest
- SPET:
-
single photon emission tomography
- TCR:
-
transmission count rate to emission crosstalk count rate
References
Abufadel A, Eisner RL, Schafer RW (2001) Differences due to collimator blurring in cardiac images with use of circular and elliptic camera orbits. J Nucl Cardiol 8:458–465
Achtert AD, King MA, Dahlberg ST, Pretorius PH, LaCroix KJ, Tsui BM (1998) An investigation of the estimation of ejection fractions and cardiac volumes by a quantitative gated SPECT software package in simulated gated SPECT images. J Nucl Cardiol 5:144–152
Almeida P, Bendriem B, de Dreuille O, Peltier A, Perrot C, Brulon V (1998) Dosimetry of transmission measurements in nuclear medicine: a study using anthropomorphic phantoms and thermoluminescent dosimeters. Eur J Nucl Med 25:1435–1441
Almquist H, Arheden H, Arvidsson AH, Pahlm O, Palmer J (1999) Clinical implication of down-scatter in attenuation-corrected myocardial SPECT. J Nucl Cardiol 6:406–411
Araujo LI, Jimenez-Hoyuela JM, McClellan JR, Lin E, Viggiano J, Alavi A (2000) Improved uniformity in tomographic myocardial perfusion imaging with attenuation correction and enhanced acquisition and processing. J Nucl Med 41:1139–1144
Bai J, Hashimoto J, Suzuki T, Nakahara T, Kubo A, Iwanaga S, Mitamura H, Ogawa S (2001) Comparison of image reconstruction algorithms in myocardial perfusion scintigraphy. Ann Nucl Med 15:79–83
Bailey DL, Meikle SR (2000) Does attenuation correction work? J Nucl Med 41:960–961
Bieszk JA, Hawman EG (1987) Evaluation of SPECT angular sampling effects: continuous versus step-and-shoot acquisition. J Nucl Med 28:1308–1314
Blocklet D, Seret A, Popa N, Schoutens A (1999) Maximum-likelihood reconstruction with ordered subsets in bone SPECT. J Nucl Med 40:1978–1984
Britten AJ, Jamali F, Gane JN, Joseph AE (1998) Motion detection and correction using multi-rotation 180 degrees single-photon emission tomography for thallium myocardial imaging. Eur J Nucl Med 25:1524–1530
Bruyant PP (2002) Analytic and iterative reconstruction algorithms in SPECT. J Nucl Med 43: 1343–1358
Bural G, Ceri IO, Erkilic M, Tercan E, Saka O (2002) The change of cardiac axis in exercise and rest 99mTc MIBI scintigraphy: it’s effect on image quality during SPECT reconstruction. Eur J Nucl Med29:S177
Burger C, Berthold T (2000) Physical principles and practical aspects of clinical PET imaging. In: von Schulthness GK, Buck A, Engel-Bicik I, Steinert HC (eds) Clinical positron emission tomography. Correlation with morphological cross-sectional imaging. Lippincott Williams and Wilkins, Philadelphia
Cantinho GC, Pena HP, Monteiro JM, Daniel AD, Chester HC, Godinho FG (2002) Normal functional parameters of left ventricle in perfusion gated SPECT. Eur J Nucl Med 29: S206
Cao Z, Holder LE, Chen CC (1996) Optimal number of views in 360 degrees SPECT imaging. J Nucl Med 37:1740–1744
Catafau AM (2001) Brain SPECT in clinical practice, part I perfusion. J Nucl Med 42:259–271
Cooper JA, Neumann PH, McCandless BK (1992) Effect of patient motion on tomographic myocardial perfusion imaging. J Nucl Med 33:1566–1571
Darcourt J, Buvat I (2000) Does attenuation correction work? J Nucl Med 41:961
Dede F, Narin Y (2002) Comparison of left ventricular function at rest and post-stress Tc-99m MIBI gated SPECT in normal and ischaemic myocardium. Eur J Nucl Med 29: S210
Delbeke D, Sandler MP (2000) The role of hybrid cameras in oncology. Semin Nucl Med XXX: 268–280
DePuey EG (1994) How to detect and avoid myocardial perfusion SPECT artifacts. J Nucl Med 35: 699–702
DePuey EG, Garcia EV (2001) Updated imaging guidelines for nuclear cardiology procedures, part 1. American Society of Nuclear Cardiology. J Nucl Cardiol 8: G1–G58
Dziuk M, Canizales A, Britton KE, Pietrzykowski J, Cholewa M (2002) The comparison of adenosine exercise Tc-99m tetrafosmin with treadmill MIBI gated SPECT. Eur J Nucl Med 29: S211
Eisner RL, Nowak DJ, Pettigrew R, Fajman W (1986) Fundamentals of 180° acquisition and reconstruction in SPECT imaging. J Nucl Med 27:1717–1728
El Fakhri GN, Buvat I, Pelegrini M, Benali H, Almeida P, Bendriem B, Todd-Pokropek A, Di Paola R (1999) Respective roles of scatter, attenuation, depth-dependent collimator response and finite spatial resolution in cardiac single-photon emission tomography quantitation: a Monte Carlo study. Eur J Nucl Med 26:437–446
El Fakhri G, Buvat I, Almeida P, Bendriem B, Todd-Pokropek A, Benali H (2000a) Should scatter be corrected in both transmission and emission data for accurate quantitation in cardiac SPET? Eur J Nucl Med 27:1356–1364
El Fakhri G, Buvat I, Benali H, Todd-Pokropek A, Di Paola R (2000b) Relative impact of scatter, collimator response, attenuation, and finite spatial resolution corrections in cardiac SPECT. J Nucl Med 41:1400–1408
Fahey FH, Harkness BA, Keyes JW Jr, Madsen MT, Battisti C, Zito V (1992) Sensitivity, resolution and image quality with a multi-head SPECT camera. J Nucl Med 33:1859–1863
Fleming JS, Alaamer AS (1996) The influence of collimator characteristics on quantitation in SPECT. J Nucl Med 37:1832–1835
Ford PV, Chatziioannou SN, Moore WH, Dhekne RD (2001) Overestimation of the LVEF by quantitative gated SPECT in simulated left ventricles. J Nucl Med 42:454–459
Forstrom LA, Dunn WL, O’Connor MK, Decklever TD, Hardyman TJ, Howarth DM (1996) Technical pitfalls in image acquisition, processing and display. Semin Nucl Med XXVI: 278–294
Galt JR, Cullom SJ, Garcia EV (1992) SPECT quantification: a simplified method of scatter and attenuation correction for cardiac imaging. J Nucl Med 33:2232–2237
Galt JR, Cullom SJ, Garcia EV (1999) Attenuation and scatter compensation in myocardial perfusion SPECT. Semin Nucl Med XXIX: 204–220
Garcia EV (1994) Quantitative myocardial perfusion single-photon emission computed tomographic imaging: quo vadis? (Where do we go from here?) J Nucl Cardiol 1:83–93
Garin E, Devillers A, Girault S, Laffont S, Schill O, Bernard AM, Moisan A, Bourguet P (2001) Scinti-mammography: better detection of small-sized lesions with tomographic than planar images, a phantom study. Nucl Med Commun 22:1045–1054
Gates GF (1996) Oblique angle bone SPECT imaging of the lumbar spine, pelvis, and hips. An anatomic study. Clin Nucl Med 21:359–362
Germano G (2001) Technical aspects of myocardial SPECT imaging. J Nucl Med 42:1499–1507
Gilland DR, Tsui BMW, McCartney WH, Perry JR, Berg J (1988) Determination of the optimum filter function for SPECT imaging. J Nucl Med 29:643–650
Gillen GJ, Gilmore B, Elliott AT (1991) An investigation of the magnitude and causes of count loss artifacts in SPECT imaging. J Nucl Med 32:1771–1776
Gonzalez MJ, Ricart Y, Martin-Comin J, Pallares C, Beltran P, Gomez-Hospital J, Cequier A, Esplugas E, Ramos M (2002) LVEF, motility index and LV volumes. Gated-SPECT versus ventriculography performed within 24 hours. Eur J Nucl Med 29: S209
Gustafsson A, Arlig A, Jacobsson L, Ljungberg M, Wikkelso C (2000) Dual-window scatter correction and energy window setting in cerebral blood flow SPECT: a Monte Carlo study. Phys Med Biol 45:3431–3440
Hansen CL (2002) Digital image processing for clinicians, part II: filtering. J Nucl Cardiol 9:429–437
Hansen CL, Kramer M (2000) Attenuation smear: a ‘paradoxical’ increase in counts due to attenuation artifact. Int J Card Imaging 16:455–460
Harada M, Shimizu A, Murata M, Kubo M, Mitani R, Dairaku Y, Matsuzaki M (2002) Simultaneous evaluation of systolic and diastolic regional functions with quadruple contours display method using ECG-gated myocardial SPECT. Eur J Nucl Med 29: S211
Harel F, Genin R, Daou D, Lebtahi R, Delahaye N, Helal BO, Le Guludec D, Faraggi M (2001) Clinical impact of combination of scatter, attenuation correction, and depth-dependent resolution recovery for 201T1 studies. J Nucl Med 42:1451–1456
Hashimoto J, Kubo A, Ogawa K, Amano T, Fukuuchi Y, Motomura N, Ichihara T (1997) Scatter and attenuation correction in technetium-99m brain SPECT. J Nucl Med 38:157–162
Heikkinen J, Kuikka JT, Ahonen A, Rautio P (1998) Quality of brain perfusion single-photon emission tomography images: multicentre evaluation using an anatomically accurate three-dimensional phantom. Eur J Nucl Med 25:1415–1422
Heikkinen J, Ahonen A, Kuikka JT, Rautio P (1999) Quality of myocardial perfusion single-photon emission tomography imaging: multicentre evaluation with a cardiac phantom. Eur J Nucl Med 26:1289–1297
Heller EN, DeMan P, Liu YH, Dione DP, Zubal IG, Wackers FJ, Sinusas AJ (1997) Extracardiac activity complicates quantitative cardiac SPECT imaging using a simultaneous transmission-emission approach. J Nucl Med 38:1882–1890
Hendel RC, Corbett JR, Cullom SJ, DePuey EG, Garcia EV, Bateman TM (2002) The value and practice of attenuation correction for myocardial perfusion SPECT imaging: a joint position statement from the American Society of Nuclear Cardiology and the Society of Nuclear Medicine. J Nucl Cardiol 9:135–143 and J Nucl Med 43:273–280
Hillel PG, Hastings DL (1993) A three-dimensional second-derivative surface-detection algorithm for volume determination on SPECT images. Phys Med Biol 38:583–600
Hines H, Kayayan R, Colsher J, Hashimoto D, Schubert R, Fernando J, Simcic V, Vernon P, Sinclair RL (1999a) Recommendations for implementing SPECT instrumentation quality control. Nuclear Medicine Section — National Electrical Manufacturers Association (NEMA). Eur J Nucl Med 26: 527–532
Hines H, Kayayan R, Colsher J, Hashimoto D, Schubert R, Fernando J, Simcic V, Vernon P, Sinclair RL (1999b) National Electrical Manufacturers Association recommendations for implementing SPECT instrumentation quality control. J Nucl Med Technol 27:67–72
Hines H, Kayayan R, Colsher J, Hashimoto D, Schubert R, Fernando J, Simcic V, Vernon P, Sinclair RL (2000) National Electrical Manufacturers Association recommendations for implementing SPECT instrumentation quality control. J Nucl Med 41:383–389
Hutton B (1996) Angular sampling necessary for clinical SPECT. J Nucl Med 37:1915–1916
Hyun IY, Kim DH, Seo JK, Kwan J, Park KS, Choe W-S, Lee WH (2002) Normal parameters of left ventricular volume and ejection fraction measured by gated myocardial perfusion SPECT: comparison of Tc-99m MIBI and Tl-201. Eur J Nucl Med 29: S205
IAEA (1991) Tecdoc 602 quality control of nuclear medicine instruments. International Atomic Energy Agency, Vienna
Iida H, Narita Y, Kado H, Kashikura A, Sugawara S, Shoji Y, Kinoshita T, Ogawa T, Eberl S (1998) Effects of scatter and attenuation correction on quantitative assessment of regional cerebral blood flow with SPECT. J Nucl Med 39:181–189
IPSM (1985) Report 44 an introduction to emission computed tomography. Institute of Physical Sciences in Medicine, London
Juni JE, Waxman AD, Devous MD Sr, Tikofsky RS, Ichise M, Van Heertum RL, Holman BL, Carretta RF, Chen CC (1998) Procedure guideline for brain perfusion SPECT using technetium-99m radiopharmaceuticals. Society of Nuclear Medicine. J Nucl Med 39:923–926
Kauppinen T, Koskinen MO, Alenius S, Vanninen E, Kuikka JT (2000) Improvement of brain perfusion SPET using iterative reconstruction with scatter and non-uniform attenuation correction. Eur J Nucl Med 27:1380–1386
Kelty NL, Cao Z-J, Holder LE (1997) Technical considerations for optimal orthopedic imaging. Semin Nucl Med XXVII: 328–333
King MA, Tsui BMW, Pan T-S (1995) Attenuation compensation for cardiac single-photon emission computed tomographic imaging, part 1. Impact of attenuation and methods of estimating attenuation maps. J Nucl Cardiol 2:513–524
Knesaurek K, King MA, Glick SJ, Penney BC (1989) Investigation of causes of geometric distortion in 180° and 360° angular sampling in SPECT. J Nucl Med 30:1666–1675
Kojima A, Matsumoto M, Takahashi M, Hirota Y, Yoshida H (1989) Effect of spatial resolution on SPECT quantification values. J Nucl Med 30:508–514
Kubo N, Morita K, Katoh C, Shiga T, Konno M, Tsukamoto E, Morita Y, Tamaki N (2000) A new dynamic myocardial phantom for the assessment of left ventricular function by gated single-photon emission tomography. Eur J Nucl Med 27:1525–1530
LaCroix KJ, Tsui BM, Hasegawa BH (1998) A comparison of 180 degrees and 360 degrees acquisition for attenuation-compensated thallium-201 SPECT images. J Nucl Med 39:562–574
Lappi S, Lazzari S, Sarti G, Pieri P (2002) Assessment of geometrical distortion and activity distribution after attenuation correction: a SPECT phantom study. J Nucl Cardiol 9:508–514
Lau YH, Hutton BF, Beekman FJ (2001) Choice of collimator for cardiac SPET when resolution compensation is included in iterative reconstruction. Eur J Nucl Med 28:39–47
Li J, Jaszczack RJ, Turkington TG, Metz CE, Gilland DR, Greer KL, Coleman RE (1994) An evaluation of lesion detectability with cone-beam, fanbeam and parallel-beam collimation in SPECT by continuous ROC study. J Nucl Med 35:135–140
Links JM, DePuey EG, Taillefer R, Becker LC (2002) Attenuation correction and gating synergistical-ly improve the diagnostic accuracy of myocardial perfusion SPECT. J Nucl Cardiol 9:183–187
Liu YH, Lam PT, Sinusas AJ, Wackers FJ (2002) Differential effect of 180 degrees and 360 degrees acquisition orbits on the accuracy of SPECT imaging: quantitative evaluation in phantoms. J Nucl Med 43:1115–1124
Maniawski PJ, Morgan HT, Wackers FJT (1991) Orbit-related variation in spatial resolution as a source of artifactual defects in thallium-201 SPECT. J Nucl Med 32:871–875
Manrique A, Faraggi M, Vera P, Vilain D, Lebtahi R, Cribier A, Le Guludec D (1999) 201T1 and 99mTc-MIBI gated SPECT in patients with large perfusion defects and left ventricular dysfunction: comparison with equilibrium radionuclide angiography. J Nucl Med 40:805–809
Matsumoto N, Berman DS, Kavanagh PB, Gerlach J, Hayes SW, Lewin HC, Friedman JD, Germano G (2001) J Nucl Med 42:687–694
Matsunari I, Boning G, Ziegler SI, Kosa I, Nekolla SG, Ficaro EP, Schwaiger M (1998) Effects of misalignment between transmission and emission scans on attenuation-corrected cardiac SPECT. J Nucl Med 39:411–416
Milo T (1996) Spect image display techniques. In: Henkin RE, Boles MA, Dillehay GL, Halama JR, Karesh SM, Wagner RH, Zimmer AM (eds) Nuclear medicine. Mosby, St Louis, pp 254–259
Mueller SP, Polak JF, Kijewski MF, Holman BL (1986) Collimator selection for SPECT brain imaging: the advantage of high resolution. J Nucl Med 27:1729–1738
Mullani NA (2000) Comparing diagnostic accuracy of y camera coincidence systems and PET for detection of lung lesions. J Nucl Med 41:959–960
Muylle K, Vanhove C, Maenhout A, Franken PR (2002) Comparison of 180-degree and 360-degree data acquisition in gated myocardial perfusion and in gated blood pool tomography. Eur J Nucl Med 29:S210
Nakajima K, Taki J, Yamamoto W, Michigishi T, Tonami N (1998) Effect of 360 degrees and 180 degrees rotation SPET acquisitions on myocardial polar map: comparison of 201Tl-,99Tcm- and 123I-labelled radiopharmaceuticals. Nucl Med Commun 19:315–325
O’Connor MK (1996) Instrument- and computer-related problems and artifacts in nuclear medicine. Semin Nucl Med XXVI: 256–277
O’Connor MK, Bothun ED (1995) Effects of tomographic table attenuation on prone and supine cardiac imaging. J Nucl Med 36:1102–1106
O’Connor MK, Kelly BJ (1990) Evaluation of techniques for the elimination of “hot” bladder artifacts in SPECT of the pelvis. J Nucl Med 31:1872–1875
O’Connor MK, Brown ML, Hung JC, Hayostek RJ (1991) The art of bone scintigraphy — technical aspects. J Nucl Med 32:2332–2341
O’Connor MK, Caiati C, Christian TF, Gibbons RJ (1995) Effects of scatter correction on the measurement of infarct size from SPECT cardiac phantom studies. J Nucl Med 36:2080–2086
O’Connor MK, Kanal KM, Gebhard MW, Rossman PJ (1998) Comparison of four motion correction techniques in SPECT imaging of the heart: a cardiac phantom study. J Nucl Med 39:2027–2034
O’Connor MK, Leong LK, Gibbons RJ (2000) Assessment of infarct size and severity by quantitative myocardial SPECT: results from a multicenter study using a cardiac phantom. J Nucl Med 41: 1383–1390
Ohnishi H, Ota T, Takada M, Kida T, Noma K, Matsuo S, Masuda K, Yamamoto I, Morita R (1997) Two optimal prefilter cutoff frequencies needed for SPECT images of myocardial perfusion in a one-day protocol. J Nucl Med Technol 25:256–260
Pan TS, King MA, Der-Shan L, Dahlberg ST, Villegas BJ (1997) Estimation of attenuation maps from scatter and photopeak window single photon emission computed tomographic images of technetium 99m-labeled sestamibi. J Nucl Cardiol 4:42–51
Patton JA (2000) Instrumentation for coincidence imaging with multihead scintillation cameras. Semin Nucl Med XXX: 239–254
Pena HP, Cantinho GC, Veiga AV, Marona DM, Gomes PG, Godinho FG (2002) Perfusion gated SPECT — ejection fraction variability, as a function of the software. Eur J Nucl Med 29: S205
Peters AM, Myers MJ (1998) Physiological measurements with radionuclides in clinical practice. Oxford University Press, Oxford
Petersen CL, Kjoer A, Hviid AM (2002) Substantial difference in left ventricular architecture and perfusion can occur despite unchanged stroke volume. Eur J Nucl Med 29: S210
Piepsz A (1995) Recent advances in pediatric nuclear medicine. Semin Nucl Med XXV: 165–182
Pitman AG, Kalff V, van Every B, Risa B, Barnden LR, Kelly MJ (2002) Effect of mechanically simulated diaphragmatic respiratory motion on myocardial SPECT processed with and without attenuation correction. J Nucl Med 43:1259–1267
Port SC (1999) Imaging guidelines for nuclear cardiology procedures, part 2. American Society of Nuclear Cardiology. J Nucl Cardiol 6: G53-G84
Prvulovich EM, Jarritt PH, Vivian GC, Clarke SE, Penneil DJ, Underwood SR (1998) Quality assurance in myocardial perfusion tomography: a collaborative BNCS/BNMS audit programme. British Nuclear Cardiology Society/British Nuclear Medicine Society. Nucl Med Commun 19: 831–838
Rajabi H, Bitarafun AR, Yaghoobi N, Firouzabady H, Rustgou F (2002) Filter selection for Tc99m-sestamibi myocardial perfusion SPECT imaging. Eur J Nucl Med 29: S207
Rosenthal MS, Cullom J, Hawkins W, Moore SC, Tsui BMW, Yester M (1995) Quantitative SPECT imaging: a review and recommendations by the focus committee of the Society of Nuclear Medicine Computer and Instrumentation Council. J Nucl Med 36:1489–1513
Rubio AR, Garcia-Burillo A, Gonzalez-Gonzalez JM, Oiler G, Canela T, Richart JA, Aguade S, Roca I, Castell J (2002) Interstudy repeatability of gated-SPECT quantitative parameters. Eur J Nucl Med 29:S208
Sankaran S, Frey EC, Gilland KL, Tsui BMW (2002) Optimum compensation method and filter cutoff frequency in myocardial SPECT: a human observer study. J Nucl Med 43:432–438
Sarikaya I, Sarikaya A, Holder LE (2001) The role of single photon emission computed tomography in bone imaging. Semin Nucl Med XXXI: 3–16
Schaefer WM, Namdar T, Koch K-C, Block S, Nowak B, Buell U (2002) Validation of left ventricular ejection fraction (LVEF) by gated-99mTc-tetrofosmin-SPECT (g-SPECT) in routine clinical practice. Eur J Nucl Med 29: S207
Serrano M, Silva C, Serena A, Nogueiras JM, Vale I, Outomuro J, Campos L (2002) A simplified visual method for quantification of brain perfusion SPECT. Eur J Nucl Med 29: S194
Shen MY, Liu YH, Sinusas AJ, Fetterman R, Bruni W, Drozhinin OE, Zaret BL, Wackers FJ (1999) Quantification of regional myocardial wall thickening on electrocardiogram-gated SPECT imaging. J Nucl Cardiol 6:583–595
Starck SA, Carlsson S (1997) The determination of the effective attenuation coefficient from effective organ depth and modulation transfer function in gamma camera imaging. Phys Med Biol 42:1957–1964
Stelter P, Junik R, Krzyminiewski R, Gembicki M, Sowinski J (2001) Semiquantitative analysis of SPECT images using 99Tcm-HMPAO in the treatment of brain perfusion after the attenuation correction by the Chang method and the application of the Butterworth filter. Nucl Med Commun 22:857–865
Stodilka RZ, Kemp BJ, Msaki P, Prato FS, Nicholson RL (1998) The relative contributions of scatter and attenuation corrections toward improved brain SPECT quantification. Phys Med Biol 43: 2991–3008
Stone CD, McCormick JW, Gilland DR, Greer KL, Coleman RE, Jaszczak RJ (1998) Effect of registration errors between transmission and emission scans on a SPECT system using sequential scanning. J Nucl Med 39:365–373
Strauss HW, Miller DD, Wittry MD, Cerqueira MD, Garcia EV, Iskandrian AS, Schelbert HR, Wackers FJ (1998) Procedure guideline for myocardial perfusion imaging. Society of Nuclear Medicine. J Nucl Med 39:918–923
Tatsch K, Asenbaum S, Bartenstein P, Catafau A, Halldin C, Pilowsky LS, Pupi A (2002) European Association of Nuclear Medicine procedure guidelines for brain perfusion SPET using (99m)Tc-la-belled radiopharmaceuticals. Eur J Nucl Med 29:BP36–BP42
Taylor D (1994) Filter choice for reconstruction tomography. Nucl Med Commun 15:857–859
Tsui BM, Frey EC, LaCroix KJ, Lalush DS, McCartney WH, King MA, Gullberg GT (1998) Quantitative myocardial perfusion SPECT. J Nucl Cardiol 5:507–522
Turkington TG (2000) Attenuation correction in hybrid positron emission tomography. Semin Nucl Med XXX: 255–267
Van Laere K, Koole M, Versijpt J, Dierckx R (2001a) Non-uniform versus uniform attenuation correction in brain perfusion SPET of healthy volunteers. Eur J Nucl Med 28:90–98
Van Laere K, Koole M, Versijpt J, Vandenberghe S, Brans B, D’Asseler Y, De Winter O, Kalmar A, Dierckx R (2001b) Transfer of normal 99mTc-ECD brain SPET databases between different gamma cameras. Eur J Nucl Med 28:435–449
Vanhove C, Franken PR, Defrise M, Deconinck F, Bossuyt A (2002) Reconstruction of gated myocardial perfusion SPET incorporating temporal information during iterative reconstruction. Eur J Nucl Med 29:465–472
Vines DC, Ichise M (1999) Evaluation of differential magnification during brain SPECT acquisition. J Nucl Med Technol 27:198–203
Wackers FJT (1999) Attenuation correction, or the emperor’s new clothes (editorial). J Nucl Med 40: 1310–1312
Wackers FJ (2002) Should SPET attenuation correction be more widely employed in routine clinical practice? Against. Eur J Nucl Med 29:412–415
Wells RG, Simkin PH, Judy PF, King MA, Pretorius H, Gifford HC (1999) Effect of filtering on the detection and localization of small Ga-67 lesions in thoracic single photon emission computed tomography images. Med Phys 26:1382–1388
Wells RG, King MA, Simkin PH, Judy PF, Brill AB, Gifford HC, Licho R, Pretorius PH, Schneider PB, Seidin DW (2000) Comparing filtered backprojection and ordered-subsets expectation maximization for small-lesion detection and localization in 67Ga SPECT. J Nucl Med 41:1391–1399
Wright GA, McDade M, Keeble W, Martin W, Hutton I (2000) Quantitative SPECT myocardial perfusion imaging with 201T1: an assessment of the limitations. Nucl Med Commun 21:1147–1151
Wright GA, McDade M, Martin W, Hutton I (2002) Quantitative gated SPECT: the effect of reconstruction filter on calculated left ventricular ejection fractions and volumes. Phys Med Biol 47: N99–N105
Zaidi H, Hasegawa B (2003) Determination of the attenuation map in emission tomography. J Nucl Med 44:291–315
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Hamilton, D. (2004). Single Photon Tomographic Imaging. In: Diagnostic Nuclear Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-06588-4_16
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