Dual Photon Imaging

  • David Hamilton


Dual photon emission tomography (DPET) overcomes one of main limitations of SPET, the effect of absorptive collimation; and enhances the accuracy of the activity representation in the tomographic image by allowing accurate correction for attenuation. Its main operational difference to SPET is that it relies on two photons, from the same annihilation event, being detected in coincidence. Removal of the absorptive collimation results in better detection sensitivity and spatial resolution which is independent of depth in the patient. Although spatial resolution, in SPET, can approach comparability with DPET using focussed, e.g. fanbeam, collimators; the detection sensitivity of SPET, even with multi-detector systems, cannot approach that of dedicated 3D DPET. A major barrier, to clinical implementation of DPET, is the high cost of dedicated systems (Dilsizian et al. 2001). This can be overcome using a coincidence y camera, which can operate as both a single photon and a coincidence system (Budinger 1998). These may be the most innovative devices introduced in nuclear medicine during the last few years but are complements to, rather than competitors of, dedicated systems (Kunze et al. 2000). To achieve the required functionality, the single photon y camera requires a number of modifications.


Attenuation Correction Projection Line Random Coincidence Annihilation Photon Scatter Fraction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



two dimensions


three dimensions


attenuation correction factor


analogue to digital converter


bismuth germanate oxide


coincidence-list-ordered sets expectation-maximisation


computed tomography


dual photon emission tomography


filtered back-projection




Fourier re-binning


field of view


full width at half maximum


gadolinium oxyorthosilicate


low energy high resolution


lutetium oxyorthosilicate


multi-slice re-binning


noise equivalent count


ordered subset estimation maximisation


pulse height analyser


photomultiplier tube


single photon emission tomography


single-slice re-binning




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Copyright information

© Springer-Verlag Berlin Heidelberg 2004

Authors and Affiliations

  • David Hamilton
    • 1
  1. 1.Riyadh Al Kharj Hospital ProgrammeX990 Military HospitalRiyadhSaudi Arabia

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