Clinical Intracoronary Ultrasound

  • Jurgen Ligthart
  • Pim J. de Feyter
Part of the Medical Radiology book series (MEDRAD)


Catheter-based intracoronary imaging produces real-time high resolution cross-sectional tomographic images from lumen and vessel wall.


Intravascular Ultrasound Great Cardiac Vein External Elastic Membrane Soft Plaque Total Vessel Area 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Bartorelli AL, Neville RF, Keren G, Potkin BN, Almagor Y, Bonner RF, Gessert JM, Leon MB (1992) In vitro and in vivo intravascular ultrasound imaging. Eur Heart J 13: 102–108PubMedGoogle Scholar
  2. Bridal SL, Fornes P, Bruneval P, Berger G (1997) Parametric (integrated backscatter and attenuation) images constructed using backscattered radio frequency signal (25–56 MHz) from human aortae in vitro. Ultrasound Med Biol 23: 215–229PubMedCrossRefGoogle Scholar
  3. De Feyter PJ, Ozaki Y, Baptista J, Escaned J, Di Mario C, de Jaegere PP, Serruys PW, Roelandt JR (1995) Ischemia-related lesion characteristics in patients with stable or unstable angina. A study with intracoronary angioscopy and ultrasound. Circulation 92: 1408–1413Google Scholar
  4. Di Mario C, The SH, Madretsma S, van Suylen RJ, Wilson RA, Born N, Serruys PW, Gussenhoven EJ, Roelandt JR (1992) Detection and characterization of vascular lesions by intra-vascular ultrasound: an in vitro study correlated with histology. J Am Soc Echocardiogr 5: 135–146PubMedGoogle Scholar
  5. Fitzgerald PJ, St Goar FG, Connolly AJ, Pinto FJ, Billingham ME, Popp RL, Yock PG (1992) Intravascular ultrasound imaging of coronary arteries. Is three layers the norm? Circulation 86: 154–158PubMedCrossRefGoogle Scholar
  6. Fitzgerald PJ, Yock C, Yock PG (1998) Orientation of intracoronary ultrasonography: looking beyond the artery. J Am Soc Echocardiogr 11: 13–19PubMedCrossRefGoogle Scholar
  7. Friedrich GJ, Moes NY, Muhlberger VA, Gabl C, Mikuz G, Hausmann D, Fitzgerald PJ, Yock PG (1994) Detection of intralesional calcium by intracoronary ultrasound depends on the histologic pattern. Am Heart J 128: 435–441PubMedCrossRefGoogle Scholar
  8. Fuster V, Lewis A (1994) Conner Memorial Lecture. Mechanisms leading to myocardial infarction: insights from studies of vascular biology. Circulation 90: 2126–2146PubMedCrossRefGoogle Scholar
  9. Ge J, Liu F, Gorge G, Haude M, Baumgart D, Erbel R (1995) Angiographically `silent’ plaque in the left main coronary artery detected by intravascular ultrasound. Coron Artery Dis 6: 805–810PubMedCrossRefGoogle Scholar
  10. Gerber TC, Erbel R, Gorge G, Ge J, Rupprecht HJ, Meyer J (1994) Extent of atherosclerosis and remodeling of the left main coronary artery determined by intravascular ultrasound. Am J Cardiol 73: 666–671PubMedCrossRefGoogle Scholar
  11. Glagov S, Weisenberg E, Zarins CK, Stankunavicius R, Kolettis GJ (1987) Compensatory enlargement of human atherosclerotic coronary arteries. N Engl J Med 316: 1371–1375PubMedCrossRefGoogle Scholar
  12. Gussenhoven EJ, Essed CE, Lancee CT, Mastik F, Frietman P, van Egmond FC, Reiber J, Bosch H, van Urk H, Roelandt J et al (1989) Arterial wall characteristics determined by intravascular ultrasound imaging: an in vitro study. J Am Coll Cardiol 14: 947–952PubMedCrossRefGoogle Scholar
  13. Hausmann D, Erbel R, Alibelli-Chemarin MJ, Boksch W, Caracciolo E, Cohn JM, Culp SC, Daniel WG, de Scheerder I, DiMario C et al (1995) The safety of intracoronary ultrasound. A multicenter survey of 2207 examinations. Circulation 91: 623–630PubMedCrossRefGoogle Scholar
  14. Hausmann D, Johnson JA, Sudhir K, Mullen WL, Friedrich G, Fitzgerald PJ, Chou TM, Ports TA, Kane JP, Malloy MJ, Yock PG (1996) Angiographically silent atherosclerosis detected by intravascular ultrasound in patients with familial hypercholesterolemia and familial combined hyperlipidemia: correlation with high density lipoproteins. J Am Cardiol 27: 1562–1570CrossRefGoogle Scholar
  15. Hermiller JB, Tenaglia AN, Kisslo KB, Phillips HR, Bashore TM, Stack RS, Davidson CJ (1993) In vivo validation of compensatory enlargement of atherosclerotic coronary arteries. Am J Cardiol 71: 665–668PubMedCrossRefGoogle Scholar
  16. Hiro T, Leung CY, de Guzman S, Caiozzo VJ, Farvid AR, Karimi H, Helfant RH, Tobis JM (1997) Are soft echoes really soft ? Intravascular ultrasound assessment of mechanical properties in human atherosclerotic tissue. Am Heart J 133: 1–7PubMedCrossRefGoogle Scholar
  17. Hiro T, Fujii T, Yasumoto K, Murata T, Murashige A, Matsuzaki M (2001) Detection of fibrous cap in atherosclerotic plaque by intravascular ultrasound by use of color mapping of angle-dependent echo-intensity variation. Circulation 103: 1206–1211PubMedCrossRefGoogle Scholar
  18. Hodgson JM, Reddy KG, Suneja R, Nair RN, Lesnefsky EJ, Sheehan HM (1993) Intracoronary ultrasound imaging: correlation of plaque morphology with angiography, clinical syndrome and procedural results in patients undergoing coronary angioplasty. J Am Coll Cardiol 21: 35–44PubMedCrossRefGoogle Scholar
  19. Kimura BJ, Russo RJ, Bhargava V, McDaniel MB, Peterson KL, DeMaria AN (1996) Atheroma morphology and distribution in proximal left anterior descending coronary artery: in vivo observations. J Am Coll Cardiol 27: 825–831PubMedCrossRefGoogle Scholar
  20. Lockwood GR, Ryan LK, Gotlieb AI, Lonn E, Hunt JW, Liu P, Foster FS (1992) In vitro high resolution intravascular imaging in muscular and elastic arteries. J Am Coll Cardiol 20: 153–160PubMedCrossRefGoogle Scholar
  21. Losordo DW, Rosenfield K, Kaufman J, Pieczek A, Isner JM (1994) Focal compensatory enlargement of human arteries in response to progressive atherosclerosis. In vivo documentation using intravascular ultrasound Circulation 89: 2570–2577Google Scholar
  22. Mintz GS, Douek P, Pichard AD, Kent KM, Satler LF, Popma JJ, Leon MB (1992) Target lesion calcification in coronary artery disease: an intravascular ultrasound study. J. Am Coll Cardiol 20: 1149–1155PubMedCrossRefGoogle Scholar
  23. Mintz GS, Painter JA, Pichard AD, Kent KM, Satler LF, Popma JJ, Chuang YC, Bucher TA, Sokolowicz LE, Leon MB (1995) Atherosclerosis in angiographically “normal” coronary artery reference segments: an intravascular ultrasound study with clinical correlations. J Am Coll Cardiol 25: 1479–1485PubMedCrossRefGoogle Scholar
  24. Nishioka T, Luo H, Eigler NL, Berglund H, Kim CJ, Siegel RJ (1996) Contribution of inadequate compensatory enlargement to development of human coronary artery stenosis: an in vivo intravascular ultrasound study. J Am Coll Cardiol 27: 1571–1576PubMedCrossRefGoogle Scholar
  25. Nissen SE, De Franco AC, Tuzcu EM, Moliterno DJ (1995) Coronary intravascular ultrasound: diagnostic and interventional applications. Coron Artery Dis 6: 355–367PubMedCrossRefGoogle Scholar
  26. Pasterkamp G, Wensing PJ, Post MJ, Hillen B, Mali WP, Borst C (1995) Paradoxical arterial wall shrinkage may contribute to luminal narrowing of human atherosclerotic femoral arteries. Circulation 91: 1444–1449PubMedCrossRefGoogle Scholar
  27. Pasterkamp G, Borst C, Post MJ, Mali WP, Wensing PJ, Gussenhoven EJ, Hillen B (1996) Atherosclerotic arterial remodeling in the superficial femoral artery. Individual variation in local compensatory enlargement response. Circulation 93: 1818–1825Google Scholar
  28. Peters RJ, Kok WE, Havenith MG, Rijsterborgh H, van der Wal AC, Visser CA (1994) Histopahtologic validation of intra-coronary ultrasound imaging. J Am Soc Echocardiogr 7: 230–241PubMedGoogle Scholar
  29. Pinto FJ, Chenzbraun A, Botas J, Valantine HA, St Goar FG, Alderman EL, Oesterle SN, Schroeder JS, Popp RL (1994) Feasibility of serial intracoronary ultrasound imaging for assessment of progression of intimai proliferation in cardiac transplant recipients. Circulation 90: 2348–2355PubMedCrossRefGoogle Scholar
  30. Potkin BN, Bartorelli AL, Gessert JM, Neville RF, Almagor Y, Roberts WC, Leon MB (1990) Coronary artery imaging with intravascular high-frequency ultrasound. Circulation 81: 1575–1585PubMedCrossRefGoogle Scholar
  31. Roelandt JR, di Mario C, Pandian NG, Wenguang L, Keane D, Slager CJ, de Feyter PJ, Serruys PW (1994) Three-dimensional reconstruction of intracoronary ultrasound images. Rationale, approaches, problems and directions. Circulation 90: 1044–1055Google Scholar
  32. Schoenhagen P, Ziada KM, Kapadia SR, Crowe TD, Nissen SE, Tuzcu EM (2000) Extent and direction of arterial remodeling in stable versus unstable coronary syndromes: an intra-vascular ultrasound study. Circulation 101: 598–603PubMedCrossRefGoogle Scholar
  33. St Goar FG, Pinto FJ, Alderman EL, Fitzgerald PJ, Stinson EB, Billingham ME, Popp RL (1992) Detection of coronary atherosclerosis in young adult hearts using intravascular ultrasound. Circulation 86: 756–763CrossRefGoogle Scholar
  34. Tobis JM, Mallery J, Mahon D, Lehmann K, Zalesky P, Griffith J, Gessert J, Moriuchi M, McRae M, Dwyer ML (1991) Intra-vascular ultrasound imaging of human coronary arteries in vivo. Analysis of tissue characterizations with comparison to in vitro histological specimens. Circulation 83: 913–926Google Scholar
  35. Topol EJ, Nissen SE (1995) Our preoccupation with coronary luminology. The dissociation between clinical and angiographic findings in ischemic heart disease. Circulation 92: 2333–2342Google Scholar
  36. Von Birgelen C, de Vrey EA, Mintz GS, Nicosia A, Bruining N, Li W, Slager CJ, Roelandt JR, Serruys PW, de Feyter PJ (1997) ECG-gated three-dimensional intravascular ultrasound: feasibility and reproducibility of the automated analysis of coronary lumen and atherosclerotic plaque dimensions in humans. Circulation 96: 2944–2952CrossRefGoogle Scholar
  37. Wong CB, Porter TR, Xie F, Deligonul U (1995) Segmental analysis of coronary arteries with equivalent plaque burden by intravascular ultrasound in patients with and without angiographically significant coronary artery disease. Am J Cardiol 76: 598–601PubMedCrossRefGoogle Scholar
  38. Yeung AC, Davis SF, Hauptman PJ, Kobashigawa JA, Miller LW, Valantine HA, Ventura HO, Wiedermann J, Wilensky R (1995) Incidence and progression of transplant coronary artery disease over 1 year: results of a multicenter trial with use of intravascular ultrasound. Multicenter Intravascular Ultrasound Transplant Study Group. J Heart Lung Transplant 14: 5215–5220Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2004

Authors and Affiliations

  • Jurgen Ligthart
    • 1
  • Pim J. de Feyter
  1. 1.Thorax Center, Room Bd 381Erasmus Medical CenterRotterdamThe Netherlands

Personalised recommendations