Holmium: YAG Coronary Laser Angioplasty (HOLCA). The American Experience
The development of a clinically effective laser angioplasty system for the percutaneous recanalization of occlusive coronary artery atherosclerosis is a complex task involving the selection of an optimal laser wavelength and coupling this energy source to a delivery catheter which can safely and effectively recanalize lesions in the coronary arteries. The potential advantages of using laser energy for percutaneous revascularization of coronary artery disease include; 1) reducing the restenosis rate that occurs following balloon angioplasty in approximately one-third of patients [5, 8]; 2) reducing the frequency of abrupt artery occlusion and emergency coronary bypass grafting associated with balloon angioplasty ; and 3) extending the indications for percutaneous recanalization to patients currently considered to be poor candidates for balloon angioplasty, such as those with unfavorable lesions or diffuse disease [12, 15].
KeywordsCatheter Ischemia Aspirin Heparin Luminal
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