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Intensity-Modulated Radiation Therapy for Lymph Node Metastases in Bladder Cancer

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Clinical Target Volumes in Conformal and Intensity Modulated Radiation Therapy

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

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Abstract

Bladder cancer is a common disease, and causes significant morbidity and mortality. It is estimated that there will be 56,500 new cases diagnosed in the United States in 2002, and that 12,600 men and women will die of the disease (Jemal et al. 2002). The majority of tumors are transitional cell carcinomas that arise from the transitional epithelium of the bladder mucosa. Superficial transitional cell carcinomas account for about 75% of all cases, and have a low potential to metastasize. The remaining 25% of tumors invade the muscularis propria of the bladder wall, and frequently spread to the lymph nodes and distant sites, making muscle-invasive bladder cancer a life-threatening disease. Lymph node involvement at diagnosis is associated with a high risk of occult metastatic disease and has an ominous prognosis.

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Authors and Affiliations

  1. Department of Radiation Oncology, University of Toronto, Princess Margaret Hospital, 610 University Avenue, Toronto, Ontario, Canada, M5G 2M9

    M. Milosevic MD, M. Gospodarowicz MD, R. Bristow MD & T. Haycocks

  2. Department of Surgical Oncology and Urology, University of Toronto, Princess Margaret Hospital, 610 University Avenue, Toronto, Ontario, Canada, M5G 2M9

    M. Jewett MD

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  1. M. Milosevic MD
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  2. M. Gospodarowicz MD
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  3. M. Jewett MD
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  4. R. Bristow MD
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  5. T. Haycocks
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  1. Department of Radiation Oncology, Université Catholique de Louvain Cliniques Universitaires Saint-Luc, Avenue Hippocrate 10, UCL 10/4752, 1200, Bruxelles, Belgium

    Vincent Grégoire MD, PhD  & Pierre Scalliet MD, PhD  & 

  2. Department of Radiation Oncology, UT MD Anderson Cancer Center, 77030, Houston, TX, USA

    K. Kian Ang MD, PhD

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Milosevic, M., Gospodarowicz, M., Jewett, M., Bristow, R., Haycocks, T. (2004). Intensity-Modulated Radiation Therapy for Lymph Node Metastases in Bladder Cancer. In: Grégoire, V., Scalliet, P., Ang, K.K. (eds) Clinical Target Volumes in Conformal and Intensity Modulated Radiation Therapy. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-06270-8_8

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  • DOI: https://doi.org/10.1007/978-3-662-06270-8_8

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