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Cellular Genealogy of In-Vitro Senescence and Immortalization

  • T. Matsumura
Part of the Progress in Molecular and Subcellular Biology book series (PMSB, volume 24)

Abstract

A population of mammalian somatic cells in culture in most cases terminates its proliferation after a period of vigorous growth. Occasionally, either through the action of extraneous effectors or spontaneously, it becomes immortalized, resulting in a continuously growing cell population (Hayflick and Moorhead 1961; Todaro and Green 1963).

Keywords

Family Tree Polyploid Cell Human Diploid Cell Family Tree Analysis Proliferative Population 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1999

Authors and Affiliations

  • T. Matsumura
    • 1
  1. 1.Meiji Cell Technology CenterMeiji Milk Products Co.OdawaraJapan

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