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Clinical Impact of Reduced Blood Cell Deformability During Cardiopulmonary Bypass

  • Najib Al-Khaja
  • A. Belboul
  • B. Liu
  • D. Roberts

Abstract

During cardiopulmonary bypass (CPB), red cells are traumatized [1–3], resulting in hemolysis, reduced rheological properties, and a shortened lifespan that leads to postoperative anemia [4]. Following surgery there is a further deterioration of red cell deformability for several days [2]. The effects of this rheological disturbance on postoperative morbidity has been suspected recently. In this study, red cell filtrability was studied in order to note if it could predict postoperative bleeding following heart operations. Such a test would help in selecting or anticipating high-risk bleeders on the basis of red cell rheological function.

Keywords

Cardiopulmonary Bypass Postoperative Bleeding Hollow Fibre Membrane Postoperative Blood Loss Cell Deformability 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • Najib Al-Khaja
    • 1
  • A. Belboul
    • 1
  • B. Liu
    • 1
  • D. Roberts
    • 1
  1. 1.Department of Thoracic and Cardiovascular SurgerySahlgreuska HospitalGöteborgSweden

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