Clinical Impact of Reduced Blood Cell Deformability During Cardiopulmonary Bypass
During cardiopulmonary bypass (CPB), red cells are traumatized [1–3], resulting in hemolysis, reduced rheological properties, and a shortened lifespan that leads to postoperative anemia . Following surgery there is a further deterioration of red cell deformability for several days . The effects of this rheological disturbance on postoperative morbidity has been suspected recently. In this study, red cell filtrability was studied in order to note if it could predict postoperative bleeding following heart operations. Such a test would help in selecting or anticipating high-risk bleeders on the basis of red cell rheological function.
KeywordsCardiopulmonary Bypass Postoperative Bleeding Hollow Fibre Membrane Postoperative Blood Loss Cell Deformability
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