Aprotinin: Effect on “Re-Do” Surgery

  • D. N. Ross
  • J. C. Simpson
Conference paper


The present early surgical treatment of congenital cardiac disease by palliative surgery in infancy entails the need for re-operation in later years. This is especially true of surgical treatment of congenital aortic stenosis and pulmonary atresia. The former condition can be palliated by aortic valvotomy — using inflow occlusion techniques — and the latter by modified Blalock shunt. In each case the infant is palliated to allow growth and thus a definitive repair of the diseased outflow tract.


Outflow Tract Ventricular Outflow Tract Pulmonary Atresia Fibrin Degradation Product Aortic Root Replacement 
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  1. 1.
    Bidstrup BP, Royston D, Sapsford RN, Taylor KM (1989) Reduction in blood loss and blood use after cardiopulmonary bypass with high-dose aprotinin. J Thorac Cardiovasc Surgery 97: 364–373Google Scholar
  2. 2.
    Somerville J, Ross DN (1972) Long-term results of complete correction with homograft reconstruction in pulmonary outflow tract atresia. Br Heart J 34: 29–36PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • D. N. Ross
    • 1
  • J. C. Simpson
    • 1
  1. 1.National Heart HospitalLondonUK

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