Control of Cell Polarity and Shape

  • Yi-Jun Sheu
  • Michael Snyder
Part of the The Mycota book series (MYCOTA, volume 8)


Cell polarity results from asymmetric cell growth (polarized growth) and cell division from a specific plane (polarized division), two phenomena fundamental for the development of organisms ranging from yeasts to humans. Polarized growth leads to the formation of unique cell shapes and subcellular structures required for many cell types to carry out specialized functions. Sensory transduction by the neurites of neurons, nutrient absorption by the microvilli of intestinal epithelial cells and plant fertilization by navigation of pollen tubes are examples of cellular processes that require polarized growth (Mooseker 1985; Bedinger et al. 1994; Eisen 1994). The ability to undergo morphological change is essential for the virulence of many pathogenic fungi (Shepherd 1988; see also Chap. 5, this Vol.). Appropriate division plane selection is important for the equal distribution of essential organelles, such as the nucleus and mitochondria, as well as the generation of differential cell fates.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2001

Authors and Affiliations

  • Yi-Jun Sheu
    • 1
  • Michael Snyder
    • 1
  1. 1.Department of Molecular, Cellular and Developmental BiologyYale UniversityNew HavenUSA

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