Abstract
The large amounts of biological information, linked to proteomes by means of the amino acid sequence, produce a need for algorithms that automate the use of functional descriptors. A requirement for functional computation is the availability of fully controlled descriptive terms (Karp 2000). Examples of basic computational tasks requiring functional terms are queries that use descriptions of a gene product, a cellular component, or a biological process to determine functional equality, predict new functions, reconstruct metabolic pathways, define gene expression profiles or recreate protein interaction maps.
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Ayoubi, P. et al. (2004). Gene Ontology for Filamentous Fungi. In: Brambl, R., Marzluf, G.A. (eds) Biochemistry and Molecular Biology. The Mycota, vol 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-06064-3_3
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DOI: https://doi.org/10.1007/978-3-662-06064-3_3
Publisher Name: Springer, Berlin, Heidelberg
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