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Endokrine Gewebe I: Grundlagen der endokrinen Regulation von Lebensvorgängen

  • Georg Löffler
Part of the Springer Lehrbuch book series (SLB)

Zusammenfassung

Die zellulären Funktionen höherer Organismen müssen besonders genau reguliert werden, damit die Funktionsfähigkeit des Organismus bei unterschiedlichen Umweltbedingungen erhalten werden kann. Eine entscheidende Rolle hierbei spielt das endokrine System. Es besteht aus endokrinen Drüsen, welche Hormone in die Blutbahn abgeben, die dort ihre Zielzellen finden. Entwicklungsgeschichtlich älter ist das System der Gewebshormone und der Zytokine, die für autokrine und parakrine Signalvermittlungen zuständig sind. Die Identifizierung und Charakterisierung der von Hormonen und Zytokinen benutzten Signaltransduktionswege haben in jüngster Zeit neue Erkenntnisse über die Regulation des Zellstoffwechsels erbracht. Störungen der Funktion des endokrinen Systems führen zu klinisch gut definierten Krankheitsbildern. In zunehmendem Maße stellen sich darüber hinaus viele scheinbar nicht endokrine Krankheitsbilder als Konsequenzen einer gestörten Regulation durch Zytokine oder Gewebshormone dar, so daß diesem System eine zunehmende klinische Bedeutung zukommt.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1998

Authors and Affiliations

  • Georg Löffler

There are no affiliations available

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