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Structure and Function of Cholera Toxin and Related Enterotoxins

  • Chapter
Bacterial Protein Toxins

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 145))

Abstract

Vibrio cholerae and enterotoxigenic Escherichia coli (ETEC) both cause diarrheal disease and represent a major health problem, especially among children in developing countries. Cholera is one of the great epidemic diseases; seven pandemics have been recorded in history, the last three of which are known to be due to V. cholerae serogroup O1. In 1992, a new cholera epidemic emerged, caused by the new serotype V. cholerae 0139 Bengal (Albert 1994). The new epidemic quickly spread through India and Bangladesh.

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  1. F. van den Akker
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  1. Institut für Pharmakologie und Toxikologie, Albert-Ludwigs-Universität Freiburg, Hermann-Herder-Str. 5, 79104, Freiburg i. Br., Germany

    Klaus Aktories  & Ingo Just  & 

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van den Akker, F., Merritt, E., Hol, W.G.J. (2000). Structure and Function of Cholera Toxin and Related Enterotoxins. In: Aktories, K., Just, I. (eds) Bacterial Protein Toxins. Handbook of Experimental Pharmacology, vol 145. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-05971-5_6

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