Structure and Function of Cholera Toxin and Related Enterotoxins

  • F. van den Akker
  • E. Merritt
  • W. G. J. Hol
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 145)


Vibrio cholerae and enterotoxigenic Escherichia coli (ETEC) both cause diarrheal disease and represent a major health problem, especially among children in developing countries. Cholera is one of the great epidemic diseases; seven pandemics have been recorded in history, the last three of which are known to be due to V. cholerae serogroup O1. In 1992, a new cholera epidemic emerged, caused by the new serotype V. cholerae 0139 Bengal (Albert 1994). The new epidemic quickly spread through India and Bangladesh.


Cholera Toxin Pertussis Toxin Nicotinamide Adenine Dinucleotide Diphtheria Toxin Bacterial Protein Toxin 
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© Springer-Verlag Berlin Heidelberg 2000

Authors and Affiliations

  • F. van den Akker
  • E. Merritt
  • W. G. J. Hol

There are no affiliations available

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