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Lokalanästhetika

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Zusammenfassung

Aminoamidlokalanästhetika (AALA, Lidocaintyp) und Aminoesterlokalanästhetika (AELA, Procaintyp), beide

  1. 1.

    blockieren Na+-Kanäle

  2. 2.

    besetzen Rezeptoren auf der Zytosolseite des Na+-Kanals

  3. 3.

    haben ähnliche Plasmahalbwertszeiten (Plasma-HWZ)

  4. 4.

    werden hauptsächlich in der Leber metabolisiert

  5. 5.

    können Methämoglobinämien verursachen

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Literatur

  • Barash PG, Cullen BF, Stoelting RK (1989) Clinical anesthesia. Lippincott, Philadelphia, pp 371–403

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  • Covino BG (1987) How local anesthetics work and what is their toxicity. ASA Annual Refresher Course Lectures, Atlanta, # 116

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  • Stoelting RK (1987) Pharmakology and physiology in anesthetic practice. Lippincott, Philadelphia, pp 148–168

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© 1991 Springer-Verlag Berlin Heidelberg

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Petroianu, G., Osswald, P.M. (1991). Lokalanästhetika. In: Anästhesie in Frage und Antwort. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-05717-9_70

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  • DOI: https://doi.org/10.1007/978-3-662-05717-9_70

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-53842-4

  • Online ISBN: 978-3-662-05717-9

  • eBook Packages: Springer Book Archive

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