Zusammenfassung
In jedem menschlichen Auge finden sich mit dem Alter vielfältige Veränderungen im Bereich der äußeren Netzhautschichten, der Bruch-Membran und der Aderhaut. Allerdings entwickeln sich nicht immer — zumindest bei der heutigen Lebenserwartung — Befunde, die über normale Alterungsprozesse hinaus als altersabhängige Makuladegeneration mit z.T. gravierenden funktionellen Einbußen zu klassifizieren wären. Daher sind neben solchen unspezifischen Alterungsprozessen auf molekularer und zellulärer Ebene offensichtlich noch andere, individuelle Faktoren einschließlich endogener und exogener Faktoren von Bedeutung.
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Holz, F.G., Schütt, F., Pauleikhoff, D., Bird, A.C. (2004). Pathophysiologie. In: Altersabhängige Makuladegeneration. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-05681-3_3
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