Zusammenfassung
Die Entwicklung und der Einsatz neuer Techniken in der Zellbiologie, Immunologie und Genetik hat in den letzten Jahrzehnten zu einer erheblichen Kenntniszunahme geführt, die jetzt in einem besseren Verständnis der zellulären und molekularen Mechanismen immunologischer Erkrankungen ihren Niederschlag findet. Die Anwendung dieser Erkenntnisse auf die Erkrankung des atopischen Formenkreises führen zu einem besseren Verständnis der dynamischen Prozesse, die im Rahmen der Sensibilisierung und der Ausbildung der akuten und chronischen Entzündungsreaktionen ablaufen. Auch die Mechanismen der Früh- und Spätphase der Typ-I-Reaktionen sind heute zu einem großen Teil entschlüsselt. Das folgende Kapitel soll einen Überblick über die wichtigsten Mitspieler in diesem komplexen und dynamischen Geflecht geben. In den Folgeabschnitten werden die wichtigsten Einzelkomponenten im Detail charakterisiert.
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Renz, H. et al. (1998). Molekulare und immunologische Grundlagen allergischer Erkrankungen. In: Heppt, W., Renz, H., Röcken, M. (eds) Allergologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-05660-8_3
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