On the Calculation of the Compressibility from Ultrasonic Velocity

  • Helge Pfeiffer
  • Karel Heremans
Conference paper


The adiabatic compressibility of liquids can be determined by measurements of the sound velocity and the density, quantities that are re­lated by the Newton-Laplace equation. In order to interpret the apparent compressibility of solutes in highly diluted solutions one must know the re­lation between the compressibility and the sound velocity of the solution un­der ideal conditions. The usual model is the Urick equation which assumes the validity of the Newton-Laplace equation for mixtures and the ideal addi­tivity of the adiabatic compressibilities. However, there are a number of dif­ferent models for the additivity of the sound velocity which are based on as­sumptions that are inconsistent with the Urick model. We revisit some approaches and discuss the consequences for the calculation of the com­pressibility of proteins.


Hydration Sodium Chloride Glycine Alanine Compressibility 


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Copyright information

© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • Helge Pfeiffer
    • 1
  • Karel Heremans
    • 1
  1. 1.Department of ChemistryKatholieke Universiteit LeuvenLeuvenBelgium

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