Nuclear Perturbations Following Adenovirus Infection

  • W. C. Russell
  • D. A. Matthews
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 272)


Adenoviruses are processed and assembled in the nuclei of infected cells and thereby produce significant perturbations to their structure and function. As the complex interactions that occur in the nuclei of uninfected cells are not yet fully understood many of the changes seen on infection have been described mainly in morphological terms. This chapter attempts to place more recent findings into this context and demonstrates that adenoviruses are able to hijack many cellular processes and enzymes to their advantage. In particular, modifications to nuclear PODs and nucleoli have more recently been explored in greater detail.


Nuclear Matrix Adenovirus Infection Nucleolar Protein Protein Versus rRNA Synthesis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • W. C. Russell
    • 1
  • D. A. Matthews
    • 2
  1. 1.University of St Andrews, FifeFifeScotland, UK
  2. 2.Department of Pathology and MicrobiologySchool of Medical Sciences, University Walk, Bristol UniversityBristolUK

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