Abstract
Glial Fibrillary Acid Protein (GFAP) is regarded as an astroglial-specific component and its presence can therefore be used to control the degree of differentiation of glial elements (BIGNAMI and DAHL, 1974; 1977). This method is being used with increasing frequency in neuro-oncology, with some contradictory results, however (for review see De ARMOND et al., 1980).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Bignami, A., Dahl, D.: Astrocyte-specific protein and radial glia in the cerebral cortex of newborn rat. Nature 252, 55–56 (1974)
Bignami, A., Dahl, D.: Specificity of glial fibrillary acid protein for astroglia. J. Histochem. Cytochem. 25, 466–469 (1977)
De Armond S.J., Eng, L.F., Rubinstein, L.J.: The application of glial fibrillary acidic (GFA) protein immunohistochemistry in neuro-oncology. Path. Res. Pract. 168, 374–394 (1980)
Mannoji, H., Takeshita, I., Fukui, M., Ohta, M., Kitamura, K.: Glial fibrillary acidic protein in medulloblastoma. Acta neuropath. 55, 63–69 (1981)
Palmer, J.O., Kasselberg, A.G., Netsky, M.G.: Differentiation of medulloblastoma. Studies including immuno-histochemical localization of glial fibrillary acid protein. J. Neurosurg. 55, 161–169 (1981)
Spielmeyer, W.: Histopathologie des Nervensystems. Berlin: Springer 1922
Sternberger, L.A.: Immunocytochemistry. 2nd. ed. New York, Toronto: John Wiley and Sons, 1979
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1983 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Schindler, E., Gullotta, F. (1983). Glial Fibrillary Acid Protein in Medulloblastomas. In: Jensen, HP., Brock, M., Klinger, M. (eds) Acute Non-Traumatic Intracranial Bleedings. Posterior Fossa Tumors in Infancy. Advances in Neurosurgery, vol 11. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-05589-2_31
Download citation
DOI: https://doi.org/10.1007/978-3-662-05589-2_31
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-12538-9
Online ISBN: 978-3-662-05589-2
eBook Packages: Springer Book Archive