An Angiographic Study of the Carotid Arterial System and CT Scan in the Cat After Experimentally Induced Subarachnoid Hemorrhage
The following investigations were performed to induce experimental cerebral vasospasms in cats. Three days after production of SAH 17 CT scans and angiograms were performed. Seven CT scans of cats showed a hypodense area in the right hemisphere especially in those animals in which the cerebral angiograms revealed constricted cerebral vessels possibly indicating a recent ischemic infarct or cerebral edema.
Today it is almost no problem to clip cerebral aneurysms two days after SAH in grade I — II (III patients (HUNT and HESS). But grade IV — V patients are still in a very dangerous situation, often dying before the aneurysm can be successfully dealt with.
Autopsies after death due to SAH showed that ischemia is undoubtedly the principal cause of brain damage in the acute stage of SAH.
Cerebral vasospasm is one of the main factors causing neurological deficits in man (1–5).
The following investigations in animals were performed to induce cerebral vasospasm experimentally in cats and to study the physiological pathology of severe SAH.
KeywordsCerebral Edema Cerebral Aneurysm Systemic Blood Pressure Cerebral Vasospasm Cerebral Vessel
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